Version 2.80

Term Description

This term is built for but not restricted in use to a test that measures the mean fluorescent intensity (MFI) on platelets after binding of a specific fluorochrome labeled antibody.

Part Descriptions

LP410814-0   Platelet CD41
The ITGA2B gene (integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)) [HGNC Gene ID:6138] is located on chromosome 17q21.32. ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3674] Source: National Center for Biotechnology Information (NCBI) Gene

LP20078-9   CD41
Found on Platelets and megakaryocytes
Associated with AML M7. Absent in Glanzmann's thrombasthenia Source: Regenstrief LOINC

LP20078-9   CD41
Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), also known as ITGA2B, is a human gene.

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Mutations that interfere with this role result in thrombasthenia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , CD41

Fully-Specified Name

Component
Platelet CD41 actual/normal
Property
RelRto
Time
Pt
System
Bld
Scale
Qn
Method
Flow cytometry

Additional Names

Long Common Name
Platelet CD41 actual/normal in Blood by Flow cytometry (FC)
Short Name
Plt CD41 Act/Nor Bld FC
Display Name
Platelet CD41 actual/normal FC (Bld) [Relative ratio]
Consumer Name Alpha Get Info
Platelet CD41 actual/normal, Blood

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
93320-0 Platelet surface glycoprotein disorders panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Αιμοπετάλιο CD41 πραγματικό/φυσιολογικό:RelRto:Pt:Αίμα:Qn:Κυτταρομετρία ροής
Synonyms: CD41 RelRto Αιμοπετάλιο Αιμοπετάλιο CD41
es-ES Spanish (Spain) CD41 plaquetario actual/normal:Ratio relativo:Punto temporal:Sangre:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Plaquetas CD41 real / normal:Razón relativa:Punto temporal:Sangre:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) Plaquettes CD41 MFI:Ratio relatif:Ponctuel:Sang:Numérique:Cytométrie de flux
it-IT Italian (Italy) Piastrine CD41 effettivo/normale:RelRto:Pt:Sangue:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Modelli di superficie cellulare Piastrine Punto nel tempo (episodio) Rapporto Relativo Sangue
pl-PL Polish (Poland) Płytkowy antygen CD41 badane/prawidłowe:współczynnik względny:punkt w czasie:krew:ilościowy:cytometria przepływowa (FC)
zh-CN Chinese (China) 血小板 CD41 实际的/正常的:相对比率:时间点:全血:定量型:流式细胞测量术
Synonyms: alpha IIb 整合素链 GPⅡb GPIIb α Ⅱb 整合素链 动态 发现于血小板和巨核细胞之上。与急性髓系白血病 M7（AML M7）相关。血小板无力症（Glanzmann's thrombasthenia，GT，Glanzmann 血小板机能不全，血小板衰弱症）时缺如。 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实测值 实测值/正常值;实际/正常;实际值/正常值;实际测定值/正常值 实测的 实际值 对照 对照标准 对照物 对照的 时刻;随机;随意;瞬间 来自于不同体系的两种分析物之比;相对比;相对比值 正常的 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 糖蛋白 ⅡB 糖蛋白 IIB 糖蛋白 IIB（Glycoprotein IIB，GPIIb） 细胞标志物 血;血液 血栓细胞

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93319-2