93418-2

(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript [Presence] in Tissue by Molecular genetics method

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Term Description

Testing is performed to detect HEY1-NCOA2 gene fusion transcripts in tissue (tumor) specimens by various molecular pathology methods for the diagnosis of mesenchymal chondrosarcoma, a rare sarcoma of bone and soft tissue.

Part Description

LP411313-2 (8;8)(q13;q21)(HEY1,NCOA2)
The HEY1-NCOA2 (8;8)(q13;q21) fusion transcript is associated with mesenchymal chondrosarcoma, a rare sarcoma of bone and soft tissues that account for 2-10% of primary chondrosarcomas. Wang et al found that 10 out of 15 examined mesenchymal chondrosarcomas carried the in-frame fusion of HEY1 to NCOA2. They suggested the fusion may occur due to an interstitial deletion or a t(8;8)(q13;q21) chromosomal translocation since both genes are located on the long arm of chromosome 8. PMID: 22034177 Source: Regenstrief LOINC

Fully-Specified Name

Component: (8;8)(q13;q21)(HEY1,NCOA2) fusion transcript
Property: PrThr
Time: Pt
System: Tiss
Scale: Ord
Method: Molgen

Additional Names

Long Common Name: (8;8)(q13;q21)(HEY1,NCOA2) fusion transcript [Presence] in Tissue by Molecular genetics method
Short Name: (8;8)(HEY1,NCOA2) Tiss Ql
Display Name: (8;8)(q13;q21)(HEY1,NCOA2) fusion transcript Molgen Ql (Tiss)
Consumer Name Alpha Get Info: (8;8)(q13;q21)(HEY1,NCOA2) fusion transcript analysis, Tissue

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.67
Last Updated: Version 2.67 (ADD)
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	(8;8)(q13;q21)(HEY1,NCOA2) μεταγραφή συγχώνευσης:PrThr:Pt:Ιστός:Ord:Μοριακή γενετική Synonyms: (8;8)(q13;q21)(HEY1,NCOA2) PrThr
es-ES	Spanish (Spain)	(HEY1, NCOA2) (8; 8) (q13; q21) Tránscritos de fusión:PrThr:Punto temporal:Tejido:Ord:Genética molecular
es-MX	Spanish (Mexico)	(8; 8) (q13; q21) (HEY1, NCOA2) transcripción de fusión:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Genética molecular
fr-FR	French (France)	t(8;8)(q13;q21)(HEY1,NCOA2) transcrit de fusion:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Biologie moléculaire
fr-CA	French (Canada)	(8;8)(q13;q21)(HEY1,NCOA2) transcrit de fusion:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Molgen
it-IT	Italian (Italy)	(8;8)(q13;q21)(HEY1,NCOA2), trascritto di fusione:PrThr:Pt:Tessuto:Ord:Molgen Synonyms: Genetica molecolare Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
zh-CN	Chinese (China)	(8;8)(q13;q21)(HEY1,NCOA2) 融合转录物:存在情况或阈值:时间点:组织与涂片:序数型:分子遗传学类实验室方法 Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录

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Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.