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Term Description

Testing is performed to detect HEY1-NCOA2 gene fusion transcripts in tissue (tumor) specimens by various molecular pathology methods for the diagnosis of mesenchymal chondrosarcoma, a rare sarcoma of bone and soft tissue.

Part Description

LP411313-2   (8;8)(q13;q21)(HEY1,NCOA2)
The HEY1-NCOA2 (8;8)(q13;q21) fusion transcript is associated with mesenchymal chondrosarcoma, a rare sarcoma of bone and soft tissues that account for 2-10% of primary chondrosarcomas. Wang et al found that 10 out of 15 examined mesenchymal chondrosarcomas carried the in-frame fusion of HEY1 to NCOA2. They suggested the fusion may occur due to an interstitial deletion or a t(8;8)(q13;q21) chromosomal translocation since both genes are located on the long arm of chromosome 8. PMID: 22034177 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript:PrThr:Pt:Tiss:Ord:Molgen
Long Common Name
(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript [Presence] in Tissue by Molecular genetics method
Short Name
(8;8)(HEY1,NCOA2) Tiss Ql
Display Name
(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript Molgen Ql (Tiss)
Consumer Name Alpha Get Info
(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript analysis, Tissue

Part Model Get Info

  • Component
    (8;8)(q13;q21)(HEY1,NCOA2) fusion transcript
    LP411312-4
    • Analyte
      (8;8)(q13;q21)(HEY1,NCOA2) fusion transcript
      LP411312-4
      • Component Numerator
        (8;8)(q13;q21)(HEY1,NCOA2) fusion transcript
        LP411312-4
        • Component Numerator Core
          (8;8)(q13;q21)(HEY1,NCOA2)
          LP411313-2
        • Component Numerator Core Suffix
          fusion transcript
          LP150217-0
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Molgen
    LP6404-0

Example Answer List: LL744-4

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
DetectedLA11882-0
Not detectedLA11883-8

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Fúzní transkript (8;8)(q13;q21)(HEY1,NCOA2):Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Molekulární genetika
el-GRGreek (Greece)(8;8)(q13;q21)(HEY1,NCOA2) μεταγραφή συγχώνευσης:PrThr:Pt:Ιστός:Ord:Μοριακή γενετική
Synonyms: (8;8)(q13;q21)(HEY1,NCOA2) MOLPATH Ord PrThr Pt Ιστός μεταγραφή συγχώνευσης Μοριακή γενετική
es-ESSpanish (Spain)(HEY1, NCOA2) (8; 8) (q13; q21) Tránscritos de fusión:PrThr:Punto temporal:Tejido:Ord:Genética molecular
es-MXSpanish (Mexico)(8; 8) (q13; q21) (HEY1, NCOA2) transcripción de fusión:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Genética molecular
fr-FRFrench (France)t(8;8)(q13;q21)(HEY1,NCOA2) transcript de fusion:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Biologie moléculaire
fr-CAFrench (Canada)(8;8)(q13;q21)(HEY1,NCOA2) transcrit de fusion:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Molgen
it-ITItalian (Italy)(8,8)(q13,q21)(HEY1,NCOA2), trascritto di fusione:PrThr:Pt:Tessuto:Ord:Molgen
Synonyms: Genetica molecolare Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
pl-PLPolish (Poland)(8;8)(q13;q21)(HEY1,NCOA2) transkrypt fuzyjny:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:genetyka molekularna
Synonyms: diagnostyka molekularna
zh-CNChinese (China)(8;8)(q13;q21)(HEY1,NCOA2) 融合转录物:存在情况或阈值:时间点:组织与涂片:序数型:分子遗传学类实验室方法
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93418-2