Version 2.77

Term Description

Testing is performed to detect HEY1-NCOA2 gene fusion transcripts in tissue (tumor) specimens by various molecular pathology methods for the diagnosis of mesenchymal chondrosarcoma, a rare sarcoma of bone and soft tissue.
Source: Regenstrief LOINC

Part Description

LP411313-2   (8;8)(q13;q21)(HEY1,NCOA2)
The HEY1-NCOA2 (8;8)(q13;q21) fusion transcript is associated with mesenchymal chondrosarcoma, a rare sarcoma of bone and soft tissues that account for 2-10% of primary chondrosarcomas. Wang et al found that 10 out of 15 examined mesenchymal chondrosarcomas carried the in-frame fusion of HEY1 to NCOA2. They suggested the fusion may occur due to an interstitial deletion or a t(8;8)(q13;q21) chromosomal translocation since both genes are located on the long arm of chromosome 8. PMID: 22034177 Source: Regenstrief LOINC

Fully-Specified Name

Component
(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
(8;8)(HEY1,NCOA2) Tiss Ql
Display Name
(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript Molgen Ql (Tiss)
Consumer Name Alpha Get Info
(8;8)(q13;q21)(HEY1,NCOA2) fusion transcript analysis, Tissue

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) (HEY1, NCOA2) (8; 8) (q13; q21) Tránscritos de fusión:PrThr:Punto temporal:Tejido:Ord:Genética molecular
es-MX Spanish (Mexico) (8; 8) (q13; q21) (HEY1, NCOA2) transcripción de fusión:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Genética molecular
fr-FR French (France) t(8;8)(q13;q21)(HEY1,NCOA2) transcrit de fusion:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) (8;8)(q13;q21)(HEY1,NCOA2) , trascritto di fusione:PrThr:Pt:Tessuto:Ord:Molgen
Synonyms: Genetica molecolare Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
zh-CN Chinese (China) (8;8)(q13;q21)(HEY1,NCOA2) 融合转录物:存在情况或阈值:时间点:组织与涂片:序数型:分子遗传学类实验室方法
Synonyms: 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内,用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物(转录本、转录产物、转录子、转录);融合基因转录本;融合转录

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93418-2