Version 2.77

Term Description

Quantitative detection of IgG antibodies against thrombospondin type-1 domain-containing protein 7A (THSD7A) in serum or plasma by immunofluorescent methods to assist in the diagnosis of primary membranous nephropathy (pMN, also known as primary membranous flomerulonephritis, pMGN). This term was created for, but not limited in use to, the submitter's test kit, EUROIMMUN Anti-THSD7A IIFT, which provides qualitative or semiquantitative determination of IgG antibodies against THSD7A.
Source: Regenstrief LOINC

Part Descriptions

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC,

LP410867-8   Thrombospondin type I domain-containing 7A
Thrombospondin type-1 domain-containing protein 7A (THSD7A) is a membrane protein that was initially characterized in placental endothelia, but is also expressed on the basal aspect of podocytes of the kidney. It has been reported to play a role in actin cytoskeletal integrity, and its soluble form has been shown to promote endothelial cell migration and filopodia formation. Autoantibodies against THSD7A have been demonstrated to be present in a small subset of patients with idiopathic/primary membranous nephropathy (MN) who do not demonstrate antibodies against the primary target in that disease, the phospholipase A2 receptor (PLA2R) PMID: 25394321. Source: Regenstrief LOINC

Fully-Specified Name

Component
Thrombospondin type I domain-containing 7A Ab.IgG
Property
Titr
Time
Pt
System
Ser/Plas
Scale
SemiQn
Method
CBA IFA

Additional Names

Short Name
THSD7A IgG Titr SerPl CBA IFA
Display Name
THSD7A IgG Cell binding immunofluorescent assay [Titer]
Consumer Name Alpha Get Info
THSD7A IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.75
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Trombospondina de tipo I 7A que contiene el dominio IgG:Titulo / Factor de dilución:Punto temporal:Suero o Plasma:Semicuantitativo:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Trombospondina tipo I que contiene 7A Ab.IgG:Título:Punto temporal:Suero o Plasma:Cuantitativo:Ensayo inmunofluorescente de unión a células
fr-FR French (France) THSD7A anticorps IgG:Titre:Ponctuel:Sérum/Plasma:Numérique:Immunofluorescence CBA
it-IT Italian (Italy) Trombospondina di tipo 1 Ab.IgG:Titr:Pt:Siero/Plasma:SemiQn:CBA IFA
Synonyms: anticorpi IgG anticorpo Fluorescenza indiretta degli anticorpi (IFA) Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant THBS1 Titolo
zh-CN Chinese (China) I 型血小板反应蛋白 7A 域 抗体.IgG:滴定度:时间点:血清/血浆:半定量型:CBA IFA
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 I 型 免疫球蛋白 G 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 细胞结合分析免疫荧光法;CBA IFA 法 血小板反应结构域蛋白7A;含有I型血小板应答蛋白结构域的7A;THSD7A;1型血小板反应蛋白7A域;Ⅰ型血小板反应蛋白7A域 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆 间接荧光抗体 间接荧光抗体试验

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93689-8