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Part Description

LP268293-0   Trimethylamine N-oxide
Trimethylamine N-oxide (TMAO) is a colorless amine oxide that is produced from choline, betaine, and carnitine by gut microbial metabolism. Recently, elevated plasma TMAO levels in humans have been associated with risk for serious adverse cardiovascular incidents and death. Diet, the composition of gut microbial flora, and liver flavin monooxygenase activity all affect the plasma levels of TMAO. Foods that contain choline, lecithin, and carnitine, including red meat, eggs, dairy products, and salt-water fish, are sources of TMAO. TMAO alters cholesterol and bile metabolism, activates inflammatory pathways, and promotes foam cell formation. It is strongly suspected in mediating the development of type-2 diabetes mellitus. TMAO also increases with decreasing kidney function, and is associated with an increased risk of death in patients with chronic kidney disease. Treatments being explored to lower TMAO include broad-spectrum antibiotics to eliminate TMAO producing bacteria, the promotion of the growth of bacteria that utilize TMAO as a substrate, and the development of target-specific molecules. PMID: 27834801 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Trimethylamine N-oxide:Sub:Pt:Ser:Qn:
Long Common Name
Trimethylamine N-oxide [Molar amount] in Serum
Short Name
TMAO sub Ser Qn
Display Name
Trimethylamine N-oxide (S) [Molar amount]
Consumer Name Alpha Get Info
Trimethylamine n-oxide, Blood

Part Model Get Info

  • Component
    Trimethylamine N-oxide
    LP268293-0
    • Analyte
      Trimethylamine N-oxide
      LP268293-0
      • Component Numerator
        Trimethylamine N-oxide
        LP268293-0
        • Component Numerator Core
          Trimethylamine N-oxide
          LP268293-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Sub
    LP6869-4
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)أوكسيد ثلاثي ميثيل الأمين في المصل ( بتقنية الكم المولي )
cs-CZCzech (Czechia)Trimethylamin N-oxid:Lákové množství:Časový bod:Sérum:Kvantitativní:
el-GRGreek (Greece)Ν-οξείδιο της τριμεθυλαμίνης:Sub:Pt:Ορός:Qn:
Synonyms: CHEM N Pt Qn Sub Ν-οξείδιο της τριμεθυλαμίνης Ορός Τριμεθυλαμίνη
es-ESSpanish (Spain)N-óxido de trimetilamina:Cantidad de sustancia:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)N-óxido de trimetilamina:Cantidad de sustancia:Punto temporal:Suero:Cuantitativo:
fr-FRFrench (France)Triméthylamine N-oxyde:Substance:Ponctuel:Sérum:Numérique:
it-ITItalian (Italy)Trimetilammina N-ossido:Sub:Pt:Siero:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Quantità di Sostanza Siero
zh-CNChinese (China)三甲基胺 N-氧化物:物质的量:时间点:血清:定量型:
Synonyms: N 型 克分子;摩尔;物质总量（摩尔数） 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 氧化三甲胺;氧化三甲胺;三甲基胺N氧化物;CAS 62637-93-8

Example Units

UnitSource
umolExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93765-6