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Part Descriptions

LP229976-8   Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1-GluA4 (also known as GluR1-GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions. PMCID: PMC4478035 The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast. PMID: 23983888 The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia. PMID: 24707504 Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC,

LOINC Names Get Info

Fully-Specified Name
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 Ab:PrThr:Pt:Ser:Ord:CBA IFA
Long Common Name
AMPAR1 Ab [Presence] in Serum by Cell binding immunofluorescent assay
Short Name
AMPAR1 Ab Ser Ql CBA IFA
Display Name
AMPAR1 Ab Cell binding immunofluorescent assay Ql (S)
Consumer Name Alpha Get Info
AMPAR1 antibody, Blood

Part Model Get Info

  • Component
    Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 Ab
    LP241878-0
    • Analyte
      Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 Ab
      LP241878-0
      • Component Numerator
        Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 Ab
        LP241878-0
        • Component Numerator Core
          Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1
          LP229976-8
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    CBA IFA
    LP269367-1

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.69 (MIN)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG50947-7Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Alfa-amino-3-hydroxy-5-methyl-4-isoxazolepropionát receptor 1 (AMPAR 1) Ab:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:CBA imunofluorescenční test
el-GRGreek (Greece)Υποδοχέας 1 α-αμινο-3-υδροξυ-5-μεθυλο-4-ισοξαζολοπροπιονικού οξέος Αντίσωμα:PrThr:Pt:Ορός:Ord:CBA IFA
Synonyms: CBA IFA Ord PrThr Pt SERO Αντίσωμα Ορός Υποδοχέας 1 α-αμινο-3-υδροξυ-5-μεθυλο-4-ισοξαζολοπροπιονικού οξέος
es-ESSpanish (Spain)Receptor 1 de Alfa-amino-3-hidroxi-5-metil-4-isoxazolepropionato Anticuerpos:PrThr:Punto temporal:Suero:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
es-MXSpanish (Mexico)Receptor 1 Ab de alfa-amino-3-hidroxi-5-metil-4-isoxazolpropionato:Presencia o umbral:Punto temporal:Suero:Ordinal:Ensayo inmunofluorescente de unión a células
fr-FRFrench (France)AMPA récepteur 1 Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence CBA
it-ITItalian (Italy)Recettore tipo 1 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato Ab:PrThr:Pt:Siero:Ord:CBA IFA
Synonyms: AMPAR1 anticorpo Fluorescenza indiretta degli anticorpi (IFA) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
pl-PLPolish (Poland)Receptor 1 alfa-amino-3-hydroksy-5-metylo-4-izoksazolopropionowy Ab:granica wykrywalności:punkt w czasie:surowica:uporządkowany:test immunofluorescencji pośredniej (z wykorzystaniem komórek)
Synonyms: AMPAR1 Przeciwciała do AMPAR 1
zh-CNChinese (China)Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 1 抗体:存在情况或阈值:时间点:血清:序数型:CBA IFA
Synonyms: Ⅰ Ⅲ Ab;自身抗体 Alpha-氨基-3-羟基-5-甲基-4-异恶唑丙酸受体 1;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 1;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 1;AMPAR1 Hydroxy I III OH α 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 细胞结合分析免疫荧光法;CBA IFA 法 羟 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 间接荧光抗体 间接荧光抗体试验 阿尔法

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93869-6