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Part Description

LP412092-1   Acetaminophen-cysteine adduct
Acetaminophen-cysteine adduct (APAP-CYS) levels are measured in serum or plasma for the determination of liver injury due to acetaminophen-induced hepatotoxicity. PMID: 27641661 The reactive metabolite of acetaminophen, N-acetyl-p-benzoquinone imine (NAPQI), is detoxified by glutathione at therapeutic doses. However, when glutathione is depleted, the metabolite covalently binds to cysteine groups on proteins and forms a acetaminophen-cysteine conjugate (3-(cystein-S-yl)-acetaminophen, APAP-CYS), which is thought to lead to hepatotoxicity. PMID: 11901099 Source: LOINC, An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients With Acute Liver Injury or Failure

LOINC Names Get Info

Fully-Specified Name
Acetaminophen-cysteine adduct:SCnc:Pt:Ser/Plas:Qn:
Long Common Name
Acetaminophen-cysteine adduct [Moles/volume] in Serum or Plasma
Short Name
APAP-Cysteine SerPl-sCnc
Display Name
Acetaminophen-cysteine adduct [Moles/Vol]
Consumer Name Alpha Get Info
Acetaminophen-cysteine adduct, Blood

Part Model Get Info

  • Component
    Acetaminophen-cysteine adduct
    LP412092-1
    • Analyte
      Acetaminophen-cysteine adduct
      LP412092-1
      • Component Numerator
        Acetaminophen-cysteine adduct
        LP412092-1
        • Component Numerator Core
          Acetaminophen-cysteine adduct
          LP412092-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.72 (MIN)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG51381-8Acetaminophen-cysteine adduct|SCnc|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Paracetamol-cystein adukt:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Προϊόν προσθήκης ακεταμινοφαίνης-κυστεΐνης:SCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: DRUG/TOX Pt Qn SCnc Ακεταμινοφαίνη Κυστεΐνη Ορός Ορός/Πλάσμα Πλάσμα Προϊόν προσθήκης ακεταμινοφαίνης-κυστεΐνης
es-ESSpanish (Spain)Aducto de acetaminofeno-cisteína:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Aducto de acetaminofeno-cisteína:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FRFrench (France)Acétaminophène-cystéine adduit:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Acetaminofene-cisteina, addotto:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Addotto di acetaminofene-cisteina Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
pl-PLPolish (Poland)Addukt paracetamolu z cysteiną:stężenie molowe:punkt w czasie:surowica lub osocze:ilościowy:
zh-CNChinese (China)对乙酰氨基酚-半胱氨酸加合物:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: Cys;巯基丙氨酸 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 对乙酰氨基酚（扑热息痛、退热净、醋氨酚、醋胺酚）-半胱氨酸（Cys、巯基丙氨酸）加合物（加成物） 扑热息痛;退热净;退热净( 一种替代阿司匹林的解热镇痛药);醋氨酚;醋氨酚晶体化合物;醋胺酚 时刻;随机;随意;瞬间 毒品 毒品类 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

UnitSource
nmol/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93972-8