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Term Description

Detection of IgG antibodies against DFS70 (dense fine speckled 70 antigen) in serum or plasma to assist in the diagnosis of autoimmune diseases. The term was created for, but not limited in use to, the submitter's test kit, Euroimmun Anti-DFS70 ELISA (IgG), which calculates the ratio of the extinction value of the control or patient sample over the extinction value of the calibrator. A ratio of greater than or equal to 1.0 is considered positive. A negative serological result does not exclude the presence of disease.

Part Description

LP230331-3   Dense fine speckled 70 protein Ab.IgG
Antinuclear antibodies are essential to diagnose systemic autoimmune rheumatic diseases (SARDs) such as Lupus erythematosus and scleroderma. However, 20-30% of healthy people test positive for ANAs,half of which are dense fine speckled 70 protein (DFS70) antibodies. DFS70 antibodies have been found in patients with various chronic inflammatory diseases but no one disease in particular. It has been suggested that the best use for measuring DFS70 antibodies might be as a biomarker that excludes the diagnosis of SARD since DFS70 antibodies are more often found in patients without active SARD than with it. Antibody titers of DFS70 are highest in healthy young females and the titers decline as a person ages.( http://cli-online.com/featured-articles/anti-dfs70-antibodies-detection-and-significance/) Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Dense fine speckled 70 protein Ab.IgG:PrThr:Pt:Ser/Plas:Ord:IA
Long Common Name
Dense fine speckled 70 protein IgG Ab [Presence] in Serum or Plasma by Immunoassay
Short Name
DFS70 IgG SerPl Ql IA
Display Name
Dense fine speckled 70 protein IgG IA Ql
Consumer Name Alpha Get Info
Dense fine speckled 70 protein IgG antibody, Blood

Part Model Get Info

  • Component
    Dense fine speckled 70 protein Ab.IgG
    LP230331-3
    • Analyte
      Dense fine speckled 70 protein Ab.IgG
      LP230331-3
      • Component Numerator
        Dense fine speckled 70 protein Ab.IgG
        LP230331-3
        • Component Numerator Core
          Dense fine speckled 70 protein
          LP230329-7
        • Component Numerator Core Suffix
          Ab.IgG
          LP32401-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    IA
    LP217197-5

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG50952-7Dense fine speckled 70 protein Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)الكشف عن تواجد الأجسام المضادة IgG البروتينية الكثيفة والمنقطية الدقيقة 70 في المصل أو البلازما ( بتقنية المقابسة المناعية )
cs-CZCzech (Czechia)Dense fine speckled 70 protein (DFS70) IgG:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:Imunoanalýza
de-DEGerman (Germany)Dichtes fein gesprenkeltes 70-Protein (DFS70) Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Immunoassay
el-GRGreek (Greece)Πυκνή λεπτόκοκκη πρωτεΐνη 70 Αντισώματα IgG:PrThr:Pt:Ορός/Πλάσμα:Ord:IA
Synonyms: IA Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Ορός Ορός/Πλάσμα Πλάσμα Πρωτεΐνη Πυκνή λεπτόκοκκη πρωτεΐνη 70
es-ESSpanish (Spain)Proteína densa fina moteada 70 IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-MXSpanish (Mexico)Ab.IgG de proteína 70 moteada fina y densa:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
fr-FRFrench (France)DFS70 Ac IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
it-ITItalian (Italy)Proteina 70 densa fine punteggiata Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA
Synonyms: anticorpi IgG anticorpo Immunoassay Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)dense fine speckled 70 protein As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay
Synonyms: antistof; antilichaam DFS70 IA
pl-PLPolish (Poland)Gęste drobnoziarniste białko 70 Ab.IgG:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:metoda immunologiczna
Synonyms: Białko DFS70 IgG Przeciwciała do antygenu Dense fine speckled 70(DFS70) przeciwciała IgG Przeciwciała IgG do antygenu Dense fine speckled 70(DFS70)
zh-CNChinese (China)致密细斑 70 蛋白 抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 DFS70;DFS-70;DFS 70-kDa;致密精细斑点 70 蛋白 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

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