94098-1

Dense fine speckled 70 protein IgG Ab [Presence] in Serum or Plasma by Immunoassay

Active

Term Description

Detection of IgG antibodies against DFS70 (dense fine speckled 70 antigen) in serum or plasma to assist in the diagnosis of autoimmune diseases. The term was created for, but not limited in use to, the submitter's test kit, Euroimmun Anti-DFS70 ELISA (IgG), which calculates the ratio of the extinction value of the control or patient sample over the extinction value of the calibrator. A ratio of greater than or equal to 1.0 is considered positive. A negative serological result does not exclude the presence of disease.

Part Description

LP230331-3 Dense fine speckled 70 protein Ab.IgG
Antinuclear antibodies are essential to diagnose systemic autoimmune rheumatic diseases (SARDs) such as Lupus erythematosus and scleroderma. However, 20-30% of healthy people test positive for ANAs,half of which are dense fine speckled 70 protein (DFS70) antibodies. DFS70 antibodies have been found in patients with various chronic inflammatory diseases but no one disease in particular. It has been suggested that the best use for measuring DFS70 antibodies might be as a biomarker that excludes the diagnosis of SARD since DFS70 antibodies are more often found in patients without active SARD than with it. Antibody titers of DFS70 are highest in healthy young females and the titers decline as a person ages.( http://cli-online.com/featured-articles/anti-dfs70-antibodies-detection-and-significance/) Source: Regenstrief LOINC

Fully-Specified Name

Component: Dense fine speckled 70 protein Ab.IgG
Property: PrThr
Time: Pt
System: Ser/Plas
Scale: Ord
Method: IA

Additional Names

Long Common Name: Dense fine speckled 70 protein IgG Ab [Presence] in Serum or Plasma by Immunoassay
Short Name: DFS70 IgG SerPl Ql IA
Display Name: Dense fine speckled 70 protein IgG IA Ql
Consumer Name Alpha Get Info: Dense fine speckled 70 protein IgG antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.67
Last Updated: Version 2.67 (ADD)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG50952-7	Dense fine speckled 70 protein Ab.IgG\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πυκνή λεπτόκοκκη πρωτεΐνη 70 Αντισώματα IgG:PrThr:Pt:Ορός/Πλάσμα:Ord:IA Synonyms: PrThr Ανοσοσφαιρίνη G Πρωτεΐνη Πυκνή λεπτόκοκκη πρωτεΐνη 70
es-ES	Spanish (Spain)	Proteína densa fina moteada 70 IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-MX	Spanish (Mexico)	Ab.IgG de proteína 70 moteada fina y densa:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
fr-FR	French (France)	DFS70 anticorps IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
it-IT	Italian (Italy)	Proteina 70 densa fine punteggiata Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA Synonyms: anticorpi IgG anticorpo Immunoassay Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	dense fine speckled 70 protein As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay Synonyms: antistof; antilichaam DFS70 IA
zh-CN	Chinese (China)	致密细斑 70 蛋白抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 DFS70;DFS-70;DFS 70-kDa;致密精细斑点 70 蛋白 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类血清或血浆

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Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.