94290-4
Saint Louis encephalitis virus neutralizing antibody [Presence] in Specimen by Neutralization test
Active
Part Descriptions
LP14232-0 Saint Louis encephalitis virus
St. Louis Encephalitis is a disease caused by the mosquito borne St. Louis Encephalitis virus. St. Louis encephalitis virus is related to Japanese encephalitis virus. This disease mainly affects the United States. Occasional cases have been reported from Canada and Mexico.
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Source: Wikipedia, St. Louis enphalitis virus
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. [PMID: 32170698] This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. [PMID: 169804]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Saint Louis encephalitis virus Ab.Neut
- Property
- PrThr
- Time
- Pt
- System
- XXX
- Scale
- Ord
- Method
- Neut
Additional Names
- Short Name
- SLEV NAb Spec Ql Nt
- Display Name
- SLEV neut ab Neut test Ql (Specimen)
- Consumer Name Alpha
- SLEV neutralizing antibody, Specimen
Example Answer List: LL744-4
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
Detected | LA11882-0 | ||
Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.72
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
- Order vs. Observation
- Both
Member of these Groups
LOINC Group | Group Name |
---|---|
LG32753-2 | Saint Louis encephalitis virus |
Language Variants
Tag | Language | Translation |
---|---|---|
fr-FR | French (France) | Encéphalite de Saint-Louis virus Ac: |
nl-NL | Dutch (Netherlands) | Saint Louis-encefalitisvirus As.neutraliserend: Synonyms: |
zh-CN | Chinese (China) | 圣路易型脑炎病毒 抗体.中和: Synonyms: |
fr-CA | French (Canada) | Virus de l'encéphalite de Saint Louis Ac.neut: |
es-ES | Spanish (Spain) | Virus de la encefalitis de Saint Louis Anticuerpos antineutrófilos: |
it-IT | Italian (Italy) | Encefalite di Saint Louis, virus Ab.Neut: Synonyms: |
es-MX | Spanish (Mexico) | Virus de la encefalitis de Saint Louis Ab: |
LOINC Terminology Service (API) using HL7® FHIR®
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=94290-4
LOINC Copyright
Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright