Version 2.80

Term Description

A patient's genotype (e.g. S/S) for the 44-base pair promoter insertion/deletion polymorphism, 5-HTTLPR, in the SLC6A4 (solute carrier family 6 (neurotransmitter transporter), member 4) gene.

Part Description

LP417576-8   SLC6A4 gene 5-HTTLPR variant
The 5-HTTLPR variant in the SLC6A4 (solute carrier family 6 (neurotransmitter transporter), member 4) gene is a 44-base pair promoter insertion/deletion polymorphism that has been shown to affect the rate of serotonin uptake in patients. It may also play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.[NCBI Gene ID:6532] The serotonin transporter polymorphism results in either a long allele (L) or short allele (S) of the gene. The "L" allele is associated with normal levels of serotonin transporter, and the "S" allele is associated with reduced serotonin transporter levels and increased risk for depression. PMID: 17063469 Source: Regenstrief LOINC

Fully-Specified Name

Component
SLC6A4 gene 5-HTTLPR variant
Property
Geno
Time
Pt
System
Bld/Tiss
Scale
Nom
Method
Molgen

Additional Names

Long Common Name
SLC6A4 gene 5-HTTLPR variant [Genotype] in Blood or Tissue by Molecular genetics method Nominal
Short Name
SLC6A4 5-HTTLPR Geno Bld/T
Display Name
SLC6A4 gene 5-HTTLPR variant genotype Molgen (Bld/Tiss)
Consumer Name Alpha Get Info
SLC6A4 gene 5-HTTLPR variant genotype, Blood or tissue specimen

Example Answer List: LL5512-0

Source: Mayo Medical Laboratories
Answer Code Score Answer ID
L/L LA30674-8
S/L LA30675-5
S/S LA30676-3

Basic Attributes

Class
MOLPATH.PHARMG
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Γονίδιο SLC6A4 παραλλαγή 5-HTTLPR:Geno:Pt:Αίμα/Ιστός:Nom:Μοριακή γενετική
Synonyms: Geno Γονίδιο Γονίδιο SLC6A4 Γονίδιο SLC6A4 παραλλαγή 5-HTTLPR
es-ES Spanish (Spain) Variante 5-HTTLPR del gen SLC6A4:Genotipo:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-MX Spanish (Mexico) Variante 5-HTTLPR del gen SLC6A4:Genotipo:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FR French (France) SLC6A4 gène variant 5-HTTLPR:Génotype:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-IT Italian (Italy) SLC6A4, gene 5-HTTLPR, variante:Geno:Pt:Sangue/Tess:Nom:Molgen
Synonyms: Farmacogenomica Gene SLC6A4 Genetica molecolare Genotipo Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) SLC6A4-gen 5-HTTLPR variant:genotype:moment:bloed of weefsel:nominaal:moleculair genetisch onderzoek
Synonyms: molgen SLC6A4 gen
zh-CN Chinese (China) SLC6A4 基因 5-HTTLPR 变异:基因型:时间点:全血/组织:名义型:分子遗传学类实验室方法
Synonyms: 5HTT;5-HTT;5-羟色胺转运体基因;5-羟色胺转运体基因（5-hydroxytryptamine transporter gene，5-HTT gene）;5-羟色胺转运蛋白基因;hSERT;HTT;OCD1;SERT;五羟色胺转运体基因;五羟色胺转运蛋白基因;血清素转运体基因;血清素转运体基因（Serotonin transporter gene）;血清素转运蛋白基因;血清素运输蛋白基因 SLC6A4 基因 5-HTTLPR 变异（变型、变异体） 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94417-3