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Term Description

A patient's genotype (e.g. S/S) for the 44-base pair promoter insertion/deletion polymorphism, 5-HTTLPR, in the SLC6A4 (solute carrier family 6 (neurotransmitter transporter), member 4) gene.

Part Description

LP417576-8   SLC6A4 gene 5-HTTLPR variant
The 5-HTTLPR variant in the SLC6A4 (solute carrier family 6 (neurotransmitter transporter), member 4) gene is a 44-base pair promoter insertion/deletion polymorphism that has been shown to affect the rate of serotonin uptake in patients. It may also play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.[NCBI Gene ID:6532] The serotonin transporter polymorphism results in either a long allele (L) or short allele (S) of the gene. The "L" allele is associated with normal levels of serotonin transporter, and the "S" allele is associated with reduced serotonin transporter levels and increased risk for depression. PMID: 17063469 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
SLC6A4 gene 5-HTTLPR variant:Geno:Pt:Bld/Tiss:Nom:Molgen
Long Common Name
SLC6A4 gene 5-HTTLPR variant [Genotype] in Blood or Tissue by Molecular genetics method Nominal
Short Name
SLC6A4 5-HTTLPR Geno Bld/T
Display Name
SLC6A4 gene 5-HTTLPR variant genotype Molgen (Bld/Tiss)
Consumer Name Alpha Get Info
SLC6A4 gene 5-HTTLPR variant genotype, Blood or tissue specimen

Part Model Get Info

  • Component
    SLC6A4 gene 5-HTTLPR variant
    LP417576-8
    • Analyte
      SLC6A4 gene 5-HTTLPR variant
      LP417576-8
      • Component Numerator
        SLC6A4 gene 5-HTTLPR variant
        LP417576-8
        • Component Numerator Core
          SLC6A4 gene 5-HTTLPR variant
          LP417576-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Geno
    LP345004-8
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Molgen
    LP6404-0

Example Answer List: LL5512-0

Source: Mayo Medical Laboratories
AnswerCodeScoreAnswer ID
L/LLA30674-8
S/LLA30675-5
S/SLA30676-3

Basic Attributes

Class
MOLPATH.PHARMG
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen SLC6A4 alela 5-HTTLPR:Genotyp:Časový bod:Krev/tkáň:Nominální:Molekulární genetika
el-GRGreek (Greece)Γονίδιο SLC6A4 παραλλαγή 5-HTTLPR:Geno:Pt:Αίμα/Ιστός:Nom:Μοριακή γενετική
Synonyms: Geno MOLPATH MOLPATH.PHARMG Nom Pt Αίμα Αίμα/Ιστός Γονίδιο Γονίδιο SLC6A4 Γονίδιο SLC6A4 παραλλαγή 5-HTTLPR Ιστός Μοριακή γενετική
es-ESSpanish (Spain)Variante 5-HTTLPR del gen SLC6A4:Genotipo:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-MXSpanish (Mexico)Variante 5-HTTLPR del gen SLC6A4:Genotipo:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FRFrench (France)SLC6A4 gène variant 5-HTTLPR:Génotype:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)SLC6A4, gene 5-HTTLPR, variante:Geno:Pt:Sangue/Tess:Nom:Molgen
Synonyms: Farmacogenomica Gene SLC6A4 Genetica molecolare Genotipo Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NLDutch (Netherlands)SLC6A4-gen 5-HTTLPR variant:genotype:moment:bloed of weefsel:nominaal:moleculair genetisch onderzoek
Synonyms: molgen SLC6A4 gen
pl-PLPolish (Poland)SLC6A4 gen 5-HTTLPR wariant:genotyp:punkt w czasie:krew lub tkanka:skala nominalna:genetyka molekularna
Synonyms: diagnostyka molekularna Gen SLC6A4 Wariant 5-HTTLPR genu SLC6A4 wynik kategorialny
zh-CNChinese (China)SLC6A4 基因 5-HTTLPR 变异:基因型:时间点:全血/组织:名义型:分子遗传学类实验室方法
Synonyms: 5HTT;5-HTT;5-羟色胺转运体基因;5-羟色胺转运体基因（5-hydroxytryptamine transporter gene，5-HTT gene）;5-羟色胺转运蛋白基因;hSERT;HTT;OCD1;SERT;五羟色胺转运体基因;五羟色胺转运蛋白基因;血清素转运体基因;血清素转运体基因（Serotonin transporter gene）;血清素转运蛋白基因;血清素运输蛋白基因 SLC6A4 基因 5-HTTLPR 变异（变型、变异体） 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94417-3