Version 2.78

Part Descriptions

LP186074-3   MS.MALDI-TOF
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. PMID: 23824373 Source: Regenstrief LOINC, PMID: 23824373

LP262556-6   Candida auris
Candida auris is a fungus that was first identified in 2009 in Japan and can cause serious infections in the blood, spinal fluid, and internal organs. This emerging fungus has spread quickly and infections have been documented all over the world. C auris is difficult to identify with the currently available phenotypic methods used by laboratories, and can be misidentified as other species of yeast. It is often resistant to multiple drugs, though resistance can differ broadly across isolates. There are currently no established breakpoints to determine susceptibility, so laboratories have relied on the breakpoints of closely related Candida species or the opinion of experts in mycology. In the United States, C auris is resistant to fluconazole in 90% of infections, to amphotericin B in 30% of infections, and to echinocandins in 5% of infections. Patients at highest risk of infection are those that have been hospitalized for a long time, those with indwelling catheters, and those who have been previously treated with antibiotic or antifungal medication. Symptoms of invasive infection include fever and chills that do not resolve after treatment with antibiotics.[https://www.cdc.gov/fungal/candida-auris/index.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Candida auris
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
MS.MALDI-TOF

Additional Names

Short Name
C auris Islt Ql MS.MALDI-TOF
Display Name
C. auris MS.MALDI-TOF Ql (Isol)
Consumer Name Alpha Get Info
Candida auris

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Candida auris:Nachweis oder Schwellenwert:Zeitpunkt:Isolat:Ordinal:MS.MALDI-TOF
Synonyms: Matrix-assisted laser desorption/ionization - Time-of-Flight-Massenspektrometrie
es-ES Spanish (Spain) Candia auris:PrThr:Punto temporal:Aislado:Ord:MS.MALDI-TOF
es-MX Spanish (Mexico) Candida auris:Presencia o umbral:Punto temporal:Aislado:Ordinal:SRA. MALDI-TOF
fr-FR French (France) Candida auris:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Spectrométrie MALDI-TOF
it-IT Italian (Italy) Candida auris:PrThr:Pt:Isolato:Ord:MS.MALDI-TOF
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) Candida auris:aanwezigheid:moment:isolaat:ordinaal:MALDI-TOF
Synonyms: massaspectometrie; Malditof
zh-CN Chinese (China) 耳道假丝酵母菌:存在情况或阈值:时间点:分离株:序数型:MS.MALDI-TOF
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基质辅助激光解吸/电离飞行时间质谱;基质辅助激光解吸电离飞行时间质谱;基质辅助激光解吸飞行时间质谱;基质辅助激光解析电离飞行时间质谱;Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry;MALDI-TOF-MS;Matrix-assisted laser desorption ionization-time of flight 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 念珠菌 念珠菌属 念珠菌病 时刻;随机;随意;瞬间 耳道念珠菌;耳念珠菌

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94419-9