94534-5

SARS-CoV-2 (COVID-19) RdRp gene [Presence] in Respiratory system specimen by NAA with probe detection

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Term Description

Qualitative detection of nucleic acids within the RdRp gene of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection. Various assays have been developed that contain primer-probe sets targeting RdRp gene. [https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance]
Source: Regenstrief LOINC

Part Description

LP417598-2   SARS coronavirus 2 RdRp gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Fully-Specified Name

Component

SARS coronavirus 2 RdRp gene

Property

PrThr

Time

Pt

System

Respiratory System Specimen

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

SARS-CoV-2 RdRp Resp Ql NAA+probe

Display Name

SARS-CoV-2 (COVID-19) RdRp gene NAA+probe Ql (Respiratory system specimen)

Consumer Name Alpha Get Info

SARS-CoV-2 (COVID-19) RdRp gene, Respiratory system specimen

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Example Answer List: LL2009-0

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.68

Last Updated

Version 2.75

Change Reason

Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;

Order vs. Observation

Both

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 2019 Novel Coronavirus
• 2019-nCoV
• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Breathing
• Corona virus
• COVID19
• COVID-19
• DNA NUCLEIC ACID PROBE
• DNA probe
• ID
• II
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Lungs
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• RS
• SARS Coronavirus 1
• SARS-CoV
• SARS-CoV-1
• SARS-CoV-2
• SARS-CoV-2 RdRp
• Screen
• SDA
• Severe Acute Respiratory Syndrome
• Spec
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification
• Viral Pneumonias
• Wuhan coronavirus

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