Version 2.77

Term Description

The nucleotide sequence for the 16S rRNA gene in a bacterial isolate. 16S rRNA gene sequencing is used in the classification of bacteria.
Source: Regenstrief LOINC

Part Descriptions

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP417990-1   Bacterial 16S rRNA gene
Sequencing of the 16S rRNA gene is commonly used for taxonomic classification and identification of bacteria. The 16S gene is approximately 1500bp long and is universal in bacteria, allowing its relationships to be measured among all bacteria. Because it is universal among all bacteria, detection of 16S RNA can also be used to estimate bacterial load. The 16S sequence has a role in identifying bacteria that are atypical or rare that are unable to be identified by phenotypic tests alone. In general there is not enough variation in 16S sequence for its use in distinguishing strains for epidemiological purposes. Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial 16S rRNA gene
Property
Seq
Time
Pt
System
Isolate
Scale
Nom
Method
Sequencing

Additional Names

Short Name
Bact 16S rRNA gene Islt-Seq
Display Name
Bacterial 16S rRNA gene sequence Nom (Isol)
Consumer Name Alpha Get Info
Bacterial 16S rRNA gene

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gen 16S de rRNA bacteriano:Secuencia de nucleótidos:Punto temporal:Aislado:Nom:Secuenciación
es-MX Spanish (Mexico) Gen de ARNr 16S bacteriano:Secuencia de nucleótidos:Punto temporal:Aislado:Nominal:Secuenciación
fr-FR French (France) Bactérie ARNr 16S gène:Séquence nucléotidique:Ponctuel:Isolat:Résultat nominal:Séquençage
it-IT Italian (Italy) Gene batterico 16S rRNA:Seq:Pt:Isolato:Nom:Sequenziamento
Synonyms: Microbiologia Punto nel tempo (episodio) Sequenza nucleotidica
nl-NL Dutch (Netherlands) bacterieel 16S rRNA-gen:nucleotidevolgorde:moment:isolaat:nominaal:sequencing
zh-CN Chinese (China) 细菌 16S rRNA 基因:序列:时间点:分离株:名义型:序列测定
Synonyms: 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 序列分析;测序 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 核苷酸序列 核蛋白体 RNA 核蛋白体 RNA（Ribosomal RNA，RRNA） 核蛋白体核糖核酸 核醣体 RNA 细菌性 细菌的 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94603-8