LOINC
Version 2.73

94676-4Dipeptidyl aminopeptidase-like protein 6 IgG Ab [Presence] in Serum by Cell binding immunofluorescent assayActive

Part Descriptions

LP230267-9   Dipeptidyl aminopeptidase-like protein 6
Dipeptidyl aminopeptidase-like protein 6 (DPPX) is a regulatory subunit of neuronal Kv4.2 potassium channel and is encoded by the DPPX gene.[PMID:25320100] DPPX is a type II membrane protein that binds to specific voltage-gated potassium channels and changes their biophysical characteristics. Alterations in the DPPX gene are associated with amyotrophic lateral sclerosis with idiopathic ventricular fibrillation. [NCBI Gene ID:1804] IgG to DPPX is a biomarker for a frequently multifocal neurological disorder that develops insidiously, can be severe, responds to immunotherapy and is likely to relapse. Clinical symptoms associated with postive DPPX IgG include encephalopathy (with cortical, cerebellar or brainstem manifestations), myelopathy and autonomic dysfunction.[PMID:25320100] Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Dipeptidyl aminopeptidase-like protein 6 Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
DPPX IgG Ser Ql CBA IFA
Display Name
Dipeptidyl aminopeptidase-like protein 6 IgG Cell binding immunofluorescent assay Ql (S)
Consumer Name Alpha
Dipeptidyl aminopeptidase-like protein 6 IgG antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Groups

LG50985-7 Dipeptidyl aminopeptidase-like protein 6 Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
二肽氨基肽酶样蛋白 6 抗体.IgG:存在情况或阈值:时间点:血清:序数型:CBA IFA
fr-FRFrench (France)
DPPX anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence CBA
it-ITItalian (Italy)
Dipeptidil aminopeptidasi-like proteina 6 Ab.IgG:PrThr:Pt:Siero:Ord:CBA IFA
es-MXSpanish (Mexico)
Proteína similar a la dipeptidil aminopeptidasa 6 Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Ensayo inmunofluorescente de unión a células
es-ESSpanish (Spain)
Proteina 6 tipo Dipeptidil aminopeptidasa IgG:PrThr:Punto temporal:Suero:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94676-4