95073-3

Histoplasma capsulatum Ag [Mass/volume] in Bronchoalveolar lavage by Immunoassay

Active

Term Description

Quantitative measurement of Histoplasma capsulatum antigens in bronchoalveolar lavage (BAL) specimens by immunoassay methods for the diagnosis and monitoring of histoplasmosis. PMID: 28275076 Monitoring of histoplasmosis is performed to diagnose relapse and help determine when treatment can be stopped.

Part Description

LP16650-1 Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Histoplasma capsulatum Ag:MCnc:Pt:BAL:Qn:IA
Long Common Name: Histoplasma capsulatum Ag [Mass/volume] in Bronchoalveolar lavage by Immunoassay
Short Name: H capsul Ag BAL IA-mCnc
Display Name: H. capsulatum Ag IA (BAL) [Mass/Vol]
Consumer Name Alpha Get Info: Histoplasma capsulatum antigen, Bronchoalveolar lavage specimen

Part Model Get Info

Component
Histoplasma capsulatum Ag
LP38409-6
- Analyte
  Histoplasma capsulatum Ag
  LP38409-6
  - Component Numerator
    Histoplasma capsulatum Ag
    LP38409-6
    - Component Numerator Core
      Histoplasma capsulatum
      LP16650-1
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
BAL
LP36498-1
- System Core
  BAL
  LP36498-1
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.68 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Histoplasma capsulatum Ag:Hmotnostní koncentrace:Časový bod:Bronchoalveolární laváž:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	Histoplasma capsulatum (Ιστόπλασμα) Αντιγόνο:MCnc:Pt:BAL:Qn:IA Synonyms: BAL Histoplasma capsulatum (Ιστόπλασμα) IA MCnc MICRO Pt Qn Αντιγόνο
es-ES	Spanish (Spain)	Histoplasma capsulatum Antígeno:Concentración de masa:Punto temporal:Lavado broncoalveolar:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Histoplasma capsulatum Ag:Concentración de masa:Punto temporal:Lavado broncoalveolar:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Histoplasma capsulatum antigeen:MCnc:Pt:BalF:Qn:IA Synonyms: Juhuslik Kvantitatiivne
fr-FR	French (France)	Histoplasma capsulatum Ag:Masse/Volume:Ponctuel:Liquide bronchoalvéolaire:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Histoplasma capsulatum Ag:Concentration de masse:Temps ponctuel:Lavage broncho-alvéolaire:Quantitatif:IA Synonyms: Antigène
fr-CA	French (Canada)	Histoplasma capsulatum, Ag:Concentration de masse:Temps ponctuel:Lavage broncho-alvéolaire:Quantitatif:IA
it-IT	Italian (Italy)	Histoplasma capsulatum, Ag:MCnc:Pt:BAL:Qn:IA Synonyms: Concentrazione di Massa Immunoassay Lavaggio Bronco Alveolare Microbiologia Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	Histoplasma capsulatum Ag:massa/volume:moment:bronchoalveolaire wassing:kwantitatief:immunoassay Synonyms: antigeen IA
ru-RU	Russian (Russian Federation)	Histoplasma capsulatum Аг:МассКонц:ТчкВрм:БАЛ:Колич:IA Synonyms: Бронхоальвеолярный лаваж Количественный Массовая концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Histoplazma Kapsulatum Ag:KütlKons:Zmlı:BAL:Kant:İA Synonyms: Antijen Bronkoalveoler lavaj İmmünölçüm, immünoassay
zh-CN	Chinese (China)	荚膜组织胞浆菌抗原:质量浓度:时间点:支气管肺泡灌洗液:定量型:免疫测定法 Synonyms: Ag 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）支气管肺泡洗液时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 皮疽组织胞浆菌 Ag 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌皮疽组织胞浆菌抗原组织胞浆菌属组织胞浆菌病美洲型组织胞浆菌 Ag 美洲型组织胞浆菌抗原荚膜组织胞浆菌 Ag 鼻疽性组织浆菌 Ag 鼻疽性组织浆菌抗原

Example Units

Unit	Source
ng/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.