95154-1

PRRSV ORF5 gene sequence homology to Prime Pac in Isolate by Sequencing

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Term Description

Percent genomic homology between a new isolated PRRS virus strain and a PPRS vaccine strain (e.g. Lelystad, Fostera, IngelvacMLV, IngelvacATP, PrimePac and Prevacent) is based on the number of matching amino acids per total amino acids sequenced in the open reading frame 5 (ORF5) gene. The more homologous the ORF5 gene sequences, the more closely the variants are related. It is thought that sequence homology between isolates and vaccines will predict vaccine efficacy, however this is currently debated since little is known about the immune response to PRRS virus.

Part Description

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Prime Pac:NFr:Pt:Isolate:Qn:Sequencing
Long Common Name: PRRSV ORF5 gene sequence homology to Prime Pac in Isolate by Sequencing
Short Name: PRRSV Prime Pac Hmlgy Islt Seq-NFr
Display Name: PRRSV ORF5 gene sequence homology to Prime Pac Sequencing (Isol)
Consumer Name Alpha Get Info: PRRSV ORF5 gene Sequence Homology to Prime Pac

Part Model Get Info

Component
Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Prime Pac
LP418148-5
- Analyte
  Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Prime Pac
  LP418148-5
  - Component Numerator
    Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Prime Pac
    LP418148-5
    - Component Numerator Core
      Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Prime Pac
      LP418148-5
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Sequencing
LP150045-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.68 (ADD)
Order vs. Observation: Both

Formula (Readable)

(# of matching amino acids/total amino acids sequenced)*100 = % homology

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	PRRSV ORF5 genová sekvence homologie s Prime Pac:Početní podíl:Časový bod:Izolát:Kvantitativní:Sekvenace
el-GR	Greek (Greece)	Ομολογία αλληλουχίας του γονιδίου ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων με το Prime Pac:NFr:Pt:Απομονωμένο στέλεχος:Qn:Αλληλούχιση Synonyms: MICRO NFr Pt Qn Αλληλουχία γονιδίου ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Αλληλούχιση Απομονωμένο στέλεχος Γονίδιο Γονίδιο ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ιός Ιός του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ομολογία αλληλουχίας του γονιδίου ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων με το Prime Pac Των χοίρων
es-ES	Spanish (Spain)	Homología de secuencia del gen ORF5 del virus del síndrome respiratorio y reproductivo porcino con Prime Pac:Fracción numérica:Punto temporal:Aislado:Qn:Secuenciación Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Homología de secuencia del gen ORF5 del virus del síndrome respiratorio y reproductivo porcino con Prime Pac:Fracción numérica:Punto temporal:Aislado:Cuantitativo:Secuenciación
it-IT	Italian (Italy)	Virus della sindrome riproduttiva e respiratoria del suino, sequenziamento del gene ORF5 a Prime Pac:NFr:Pt:Isolato:Qn:Sequenziamento Synonyms: Frazione numerica Gene ORF5 virus PRRS Microbiologia Punto nel tempo (episodio) Sequenziamento del gene ORF5 a Prime Pac virus PRRS Sequenziamento del gene ORF5 virus PRRS Virus PRRS
nl-NL	Dutch (Netherlands)	'porcine' reproductief en respiratoir syndroomvirus ORF5-gensequentie homologie met Prime Pac:getalsfractie:moment:isolaat:kwantitatief:sequencing Synonyms: porcine voortplantings- en respiratoir syndroom virus van varken; PRRSV
pl-PL	Polish (Poland)	Homologia sekwencji genu ORF5 wirusa zespołu rozrodczo-oddechowego świń do Prime Pac:frakcja liczbowa:punkt w czasie:izolat:ilościowy:sekwencjonowanie Synonyms: Gen ORF5 PRRSV Homologia sekwencji genu PRRSV ORF5 do Prime Pac Sekwencja genu ORF5 PRRSV
zh-CN	Chinese (China)	猪生殖与呼吸综合征病毒 ORF5 基因序列 Prime Pac 同源物:计数型分数:时间点:分离株:定量型:序列测定 Synonyms: Lelystad 病毒;PRRS;SIRSV;兰耳病;新猪病;母猪后期流产;猪不育和呼吸综合症;猪不育和呼吸综合症（Swine infertility and respiratory syndrome，SIRSV）;猪生殖与呼吸系统综合症;猪生殖与呼吸综合症（Porcine reproductive and respiratory syndrome，PRRS）;猪繁殖与呼吸综合征;猪蓝耳病;猪蓝色病;神秘仔猪病;神秘猪病;莱利斯塔猪病毒（Lelystad Virus，LV）;蓝耳猪病;蓝耳病;蓝色流产症 PRRSV;猪生殖呼吸综合征病毒;猪呼吸繁殖综合征病毒;猪繁殖与呼吸道综合征病毒;猪繁殖和呼吸障碍综合征;Porcine Reproductive and Respiratory Syndrome;PRRS;蓝耳病;Blue Ear Disease;可译框架;可读框;开放阅读框;开放读码框;开放读码框架;编码框;ORF;open reading frame 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体分离物;分离菌;分离菌株;隔离种群可用数量表示的;定量性;数值型;数量型;连续数值型标尺序列分析;测序微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间猪的猪科猪科的遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit	Source
%	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.