9529-9

Histoplasma capsulatum IgG Ab [Units/volume] in Serum or Plasma by Immunoassay

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Part Description

LP16650-1 Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Histoplasma capsulatum Ab.IgG:ACnc:Pt:Ser/Plas:Qn:IA
Long Common Name: Histoplasma capsulatum IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
Short Name: H capsul IgG SerPl IA-aCnc
Display Name: H. capsulatum IgG IA Qn
Consumer Name Alpha Get Info: Histoplasma capsulatum IgG antibody, Blood

Part Model Get Info

Component
Histoplasma capsulatum Ab.IgG
LP38407-0
- Analyte
  Histoplasma capsulatum Ab.IgG
  LP38407-0
  - Component Numerator
    Histoplasma capsulatum Ab.IgG
    LP38407-0
    - Component Numerator Core
      Histoplasma capsulatum
      LP16650-1
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0i
Last Updated: Version 2.73 (MIN)
Change Reason: Release 2.67: SYSTEM: Updated System from Ser to Ser/Plas since this assay can be performed on both specimens.; Previous Releases: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 19470

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Histoplasma capsulatum IgG:Arbitrární koncentrace:Časový bod:Sérum/plazma:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	Histoplasma capsulatum (Ιστόπλασμα) Αντισώματα IgG:ACnc:Pt:Ορός/Πλάσμα:Qn:IA Synonyms: ACnc Histoplasma capsulatum (Ιστόπλασμα) IA MICRO Pt Qn Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] Histoplasma capsulatum [Ac].IgG [Inmunoglobulina G]:concentración arbitraria:punto en el tiempo:suero:cuantitativo:enzimoinmunoanálisis
es-ES	Spanish (Spain)	Histoplasma capsulatum IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Histoplasma capsulatum Ab.IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Histoplasma capsulatum antikehad.IgG:Acnc:Pt:S/P:Qn:IA Synonyms: Immuunglobuliin G Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Histoplasma capsulatum, IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-FR	French (France)	Histoplasma capsulatum Ac IgG:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Histoplasma capsulatum Anticorps. IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA Synonyms: Anticorps
it-IT	Italian (Italy)	Histoplasma capsulatum Ab.IgG:ACnc:Pt:Siero/Plasma:Qn:IA Synonyms: anticorpi IgG anticorpo Concentrazione Arbitraria Immunoassay Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	히스토플라스마 캡슐라툼 항체.면역글로불린 G:임의농도:검사시점:혈청:정량:효소면역측정법
nl-NL	Dutch (Netherlands)	Histoplasma capsulatum As.IgG:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
pt-BR	Portuguese (Brazil)	Histoplasma capsulatum Ac.IgG:ACnc:Pt:Soro:Qn:Imunoensaio Synonyms: Immune globulin G; Immunoglobulin G; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
ru-RU	Russian (Russian Federation)	Histoplasma capsulatum Ат.IgG:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:IA Synonyms: Антитело Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Histoplazma Kapsulatum Ab.IgG:SçKons:Zmlı:Ser/Plaz:Kant:İA Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay
zh-CN	Chinese (China)	荚膜组织胞浆菌抗体.IgG:任意型浓度:时间点:血清/血浆:定量型:免疫测定法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间皮疽组织胞浆菌 Ab 皮疽组织胞浆菌 Ab.IgG 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌皮疽组织胞浆菌抗体皮疽组织胞浆菌抗体.IgG 组织胞浆菌属组织胞浆菌病美洲型组织胞浆菌 Ab 美洲型组织胞浆菌 Ab.IgG 美洲型组织胞浆菌抗体美洲型组织胞浆菌抗体.IgG 荚膜组织胞浆菌 Ab 荚膜组织胞浆菌 Ab.IgG 荚膜组织胞浆菌 IgG 血清或血浆鼻疽性组织浆菌 Ab 鼻疽性组织浆菌 Ab.IgG 鼻疽性组织浆菌抗体鼻疽性组织浆菌抗体.IgG

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.