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Part Descriptions

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, 17-hydroxypregnenolone (Wikipedia)

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
17-Hydroxypregnenolone:Zscore:24H:Urine:Qn:
Long Common Name
17-Hydroxypregnenolone [Z-score] in 24 hour Urine
Short Name
17OH-Preg 24h Z-score Ur
Display Name
17-Hydroxypregnenolone (24H U) [Z-score]
Consumer Name Alpha Get Info
17-Hydroxypregnenolone, Urine

Part Model Get Info

  • Component
    17-Hydroxypregnenolone
    LP17184-0
    • Analyte
      17-Hydroxypregnenolone
      LP17184-0
      • Component Numerator
        17-Hydroxypregnenolone
        LP17184-0
        • Component Numerator Core
          17-Hydroxypregnenolone
          LP17184-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Zscore
    LP164005-3
  • Time
    24H
    LP6924-7
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: Replacing the component with the scientific name, and correcting typo;
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
95556-7Adrenal cancer risk assessment and urine steroid fractions panel

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)17-alfa-hydroxypregnanolon:Z-skóre:24 hodin:Moč:Kvantitativní:
el-GRGreek (Greece)17-υδροξυπρογνενολόνη:Zscore:24H:Ούρα:Qn:
Synonyms: 17-υδροξυπρογνενολόνη 24H CHEM Qn Zscore Ούρα
es-ESSpanish (Spain)17-Hidroxipregnenolona:Puntuación Z:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)17 alfa-hidroxipregnanolona:Puntuación Z:24H:Orina:Cuantitativo:
fr-FRFrench (France)17-hydroxyprégnénolone:Z score:24H:Urine:Numérique:
it-ITItalian (Italy)17-Idrossipregnenolone:Zscore:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Z-score
nl-NLDutch (Netherlands)17-hydroxypregnenolon:Z-score:24 uur:urine:kwantitatief:
Synonyms: 24U
pl-PLPolish (Poland)17-Hydroksypregnenolon:standardowa wartość Z:24h:mocz:ilościowy:
Synonyms: 24 godziny
ru-RURussian (Russian Federation)17-Гидроксипрегненолон:Z-тест:24 часа:Моча:Колич:
Synonyms: Z-тест Фишера Количественный
tr-TRTurkish (Turkey)17-Hidroksipregnenolon:Zskoru:24Sa:İdrar:Kant:
zh-CNChinese (China)17-羟基孕烯醇酮:Z评分:24小时:尿液:定量型:
Synonyms: 17-Alpha-羟基娠烯醇酮;17-Alpha-羟基孕 5 烯 3β醇 20 酮;17-Alpha-羟基孕烯诺龙;17-Alpha-羟基孕烯醇酮;17-Alpha-羟基孕甾烯醇酮;17OH-Preg;17-α-羟基娠烯醇酮;17-α-羟基孕 5 烯 3β醇 20 酮;17-α-羟基孕烯诺龙;17-α-羟基孕烯醇酮;17-α-羟基孕甾烯醇酮;17-羟基娠烯醇酮;17-羟基孕 5 烯 3β醇 20 酮;17-羟基孕烯诺龙;17-羟基孕甾烯醇酮;17-羟娠烯醇酮;17-羟孕 5 烯 3β醇 20 酮 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 Z分;Z分值;Z分数;Z得分;Z-评分;Z评分（分值、得分、分数） 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉

Example Units

UnitSource
{Zscore}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95575-7