Version 2.78

Part Description

LP97520-8   5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 5-Alpha tetrahydrocortisol

Fully-Specified Name

Component
5-Alpha tetrahydrocortisol
Property
Zscore
Time
24H
System
Urine
Scale
Qn
Method

Additional Names

Short Name
5-A THF 24h Z-score Ur
Display Name
5-Alpha tetrahydrocortisol (24H U) [Z-score]
Consumer Name Alpha Get Info
5-Alpha tetrahydrocortisol, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
95556-7 Adrenal cancer risk assessment and urine steroid fractions panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) 5-Alfa tetrahidrocortisol:Puntuación Z:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 5-alfa tetrahidrocortisol:Puntuación Z:24H:Orina:Cuantitativo:
fr-FR French (France) 5-alpha tétrahydrocortisol:Z score:24H:Urine:Numérique:
it-IT Italian (Italy) 5-Alfa tetraidrocortisolo:Zscore:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Z-score
nl-NL Dutch (Netherlands) 5-alfa-tetrahydrocortisol:Z-score:24 uur:urine:kwantitatief:
Synonyms: 24U
ru-RU Russian (Russian Federation) 5-Альфа тетрагидрокортизол:Z-тест:24 часа:Моча:Колич:
Synonyms: Z-тест Фишера Количественный
tr-TR Turkish (Turkey) 5-Alfa tetrahidrokortizol:Zskoru:24Sa:İdrar:Kant:
zh-CN Chinese (China) 5-Alpha 四氢皮质醇:Z评分:24小时:尿液:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 5 Alpha-四氢皮质甾醇 5 Alpha-四氢皮醇 5-A 四氢皮质醇;5-α 四氢皮质醇;5-alpha（α、A） 四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇） 5α-四氢皮质甾醇 5α-四氢皮质醇 5α-四氢皮醇 THC;THF;四氢皮质甾醇;四氢皮醇 Z分;Z分值;Z分数;Z得分;Z-评分;Z评分（分值、得分、分数） α 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 阿尔法

Example Units

Unit Source
{Zscore} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95582-3