95582-3

5-Alpha tetrahydrocortisol [Z-score] in 24 hour Urine

Active

Part Description

LP97520-8 5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 5-Alpha tetrahydrocortisol

LOINC Names Get Info

Fully-Specified Name: 5-Alpha tetrahydrocortisol:Zscore:24H:Urine:Qn:
Long Common Name: 5-Alpha tetrahydrocortisol [Z-score] in 24 hour Urine
Short Name: 5-A THF 24h Z-score Ur
Display Name: 5-Alpha tetrahydrocortisol (24H U) [Z-score]
Consumer Name Alpha Get Info: 5-Alpha tetrahydrocortisol, Urine

Part Model Get Info

Component
5-Alpha tetrahydrocortisol
LP97520-8
- Analyte
  5-Alpha tetrahydrocortisol
  LP97520-8
  - Component Numerator
    5-Alpha tetrahydrocortisol
    LP97520-8
    - Component Numerator Core
      5-Alpha tetrahydrocortisol
      LP97520-8
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Zscore
LP164005-3
Time
24H
LP6924-7
- Time Core
  24H
  LP6924-7
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.69 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
95556-7	Adrenal cancer risk assessment and urine steroid fractions panel

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	5-alfa-tetrahydrokortizol:Z-skóre:24 hodin:Moč:Kvantitativní:
el-GR	Greek (Greece)	5-α-τετραϋδροκορτιζόλη:Zscore:24H:Ούρα:Qn: Synonyms: 24H 5-α-τετραϋδροκορτιζόλη CHEM Qn Zscore Ούρα Τετραϋδροκορτιζόλη
es-ES	Spanish (Spain)	5-Alfa tetrahidrocortisol:Puntuación Z:24 horas:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	5-alfa tetrahidrocortisol:Puntuación Z:24H:Orina:Cuantitativo:
fr-FR	French (France)	5-alpha tétrahydrocortisol:Z score:24H:Urine:Numérique:
it-IT	Italian (Italy)	5-Alfa tetraidrocortisolo:Zscore:24h:Urine:Qn: Synonyms: 24 Ore Chimica Z-score
nl-NL	Dutch (Netherlands)	5-alfa-tetrahydrocortisol:Z-score:24 uur:urine:kwantitatief: Synonyms: 24U
pl-PL	Polish (Poland)	5-Alfa tetrahydrokortyzol:standardowa wartość Z:24h:mocz:ilościowy: Synonyms: 24 godziny
ru-RU	Russian (Russian Federation)	5-Альфа тетрагидрокортизол:Z-тест:24 часа:Моча:Колич: Synonyms: Z-тест Фишера Количественный
tr-TR	Turkish (Turkey)	5-Alfa tetrahidrokortizol:Zskoru:24Sa:İdrar:Kant:
zh-CN	Chinese (China)	5-Alpha 四氢皮质醇:Z评分:24小时:尿液:定量型: Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 5 Alpha-四氢皮质甾醇 5 Alpha-四氢皮醇 5-A 四氢皮质醇;5-α 四氢皮质醇;5-alpha（α、A）四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇） 5α-四氢皮质甾醇 5α-四氢皮质醇 5α-四氢皮醇 THC;THF;四氢皮质甾醇;四氢皮醇 Z分;Z分值;Z分数;Z得分;Z-评分;Z评分（分值、得分、分数） α 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉阿尔法

Example Units

Unit	Source
{Zscore}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.