95638-3

California encephalitis virus neutralizing antibody [Titer] in Specimen by Neutralization test

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP33331-7 California encephalitis virus
California encephalitis virus is an arbovirus of the California (CAL) serogroup virus which belongs to the Bunyaviridae family of viruses, and the genus Orthobunyavirus. Other CAL serogroup viruses found in the United States include La Crosse virus (LACV), Jamestown Canyon virus (JCV), Snowshoe hare virus, and Trivitattus virus. California encephalitis virus was first isolated in 1943 from mosquitoes. In 1945, 3 cases were isolated in humans. The fourth case was not reported until 2001 but it was found in a coastal area of California similiar to where the first 3 cases were isolated.
PMID: 11384526 Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: California encephalitis virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut
Long Common Name: California encephalitis virus neutralizing antibody [Titer] in Specimen by Neutralization test
Short Name: CEV NAb Titr Spec Nt
Display Name: CEV neut ab Neut test (Specimen) [Titer]
Consumer Name Alpha Get Info: California encephalitis virus (CEV) neutralizing antibody, Specimen

Part Model Get Info

Component
California encephalitis virus Ab.Neut
LP430329-5
- Analyte
  California encephalitis virus Ab.Neut
  LP430329-5
  - Component Numerator
    California encephalitis virus Ab.Neut
    LP430329-5
    - Component Numerator Core
      California encephalitis virus
      LP33331-7
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG32770-6	California encephalitis virus

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus kalifornské encefalitidy Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:XXX:Semikvantitativní:Neutralizační test
el-GR	Greek (Greece)	Ιός εγκεφαλίτιδας Καλιφόρνιας Ab.Neut:Titr:Pt:XXX:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr XXX Αντίσωμα Ημιποσοτική Ιός Ιός εγκεφαλίτιδας Καλιφόρνιας Ουδετερόφιλα
es-ES	Spanish (Spain)	Virus encefalitis California Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:XXX:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Virus de la encefalitis de California Ab:Título:Punto temporal:XXX:Cuantitativo:Prueba de neutralización
fr-FR	French (France)	Encéphalite de californie virus Ac neutralisant:Titre:Ponctuel:Milieux divers:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Virus encéphalite de Californie Ac.neut:Titre:Temps ponctuel:XXX:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Encefalite californiana, virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus dell''encefalite californiana
nl-NL	Dutch (Netherlands)	Californische encephalitis virus As.neutraliserend:titer:moment:XXX:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus kalifornijskiego zapalenia mózgu Ab.Neutralizujące:miano:punkt w czasie:XXX:półilościowy:test neutralizacji Synonyms: Przeciwciała do wirusa kalifornijskiego zapalenia mózgu Przeciwciała nautralizujące do wirusa kalifornijskiego zapalenia mózgu Wirus kalifornijskiego zapalenia mózgu
zh-CN	Chinese (China)	加利福尼亚脑炎病毒抗体.中和:滴定度:时间点:XXX:半定量型:中和试验 Synonyms: Ab;自身抗体 CEV Ab CEV 抗体 CEV;加州脑炎病毒不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体加利福尼亚加利福尼亚脑炎病毒 Ab 加州加州脑炎病毒 Ab 加州脑炎病毒抗体大脑炎微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间脑炎（Encephalitis，大脑炎）脑脊髓炎脑脊髓炎（Encephalomyelitis）

Example Units

Unit	Source
{titer}	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95638-3

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.