95652-4

Venezuelan equine encephalitis virus neutralizing antibody [Titer] in Specimen by Neutralization test

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Part Descriptions

LP14289-0 Venezuelan equine encephalitis virus
Venezuelan equine encephalitis virus is a mosquito -borne viral pathogen that causes Venezuelan equine encephalitis or encephalomyelitis (VEE). VEE can effect all equine species, such as horses, asses, and zebras. After infection, equines may suddenly die or show progressive central nervous system disorders. Humans also can contract this disease. Healthy adults who become infected by the virus may experience flu -like symptoms, such as high fevers and headaches. People with weakened immune systems and the young and the elderly can become severely ill or die from this disease. The virus that causes VEE is transmitted primarily by mosquitoes that bite an infected animal and then bite and feed on another animal or human. The speed with which the disease spreads depends on the subtype of the VEE virus and the density of mosquito populations. Enzootic subtypes of VEE are diseases endemic to certain areas. Generally these serotypes do not spread to other localities. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Venezuelan equine encephalitis virus (Wikipedia)

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Venezuelan equine encephalitis virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut
Long Common Name: Venezuelan equine encephalitis virus neutralizing antibody [Titer] in Specimen by Neutralization test
Short Name: VEEV NAb Titr Spec Nt
Display Name: VEEV neut ab Neut test (Specimen) [Titer]
Consumer Name Alpha Get Info: VEEV neutralizing antibody, Specimen

Part Model Get Info

Component
Venezuelan equine encephalitis virus Ab.Neut
LP430481-4
- Analyte
  Venezuelan equine encephalitis virus Ab.Neut
  LP430481-4
  - Component Numerator
    Venezuelan equine encephalitis virus Ab.Neut
    LP430481-4
    - Component Numerator Core
      Venezuelan equine encephalitis virus
      LP14289-0
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus venezuelské koňské encefalitidy (VEE) Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:XXX:Semikvantitativní:Neutralizační test
el-GR	Greek (Greece)	Ιός εγκεφαλίτιδας των ίππων της Βενεζουέλας Ab.Neut:Titr:Pt:XXX:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr XXX Αντίσωμα Ημιποσοτική Ιός Ιός εγκεφαλίτιδας των ίππων της Βενεζουέλας Ουδετερόφιλα
es-MX	Spanish (Mexico)	Virus de la encefalitis equina venezolana Ab:Título:Punto temporal:XXX:Cuantitativo:Prueba de neutralización
es-ES	Spanish (Spain)	Virus de la encefalitis equina venezolana Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:XXX:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
fr-FR	French (France)	Virus de l'encéphalite équine vénézuélienne Ac neutralisant:Titre:Ponctuel:Milieux divers:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Virus de l'encéphalite équine du Vénézuela Ac.neut:Titre:Temps ponctuel:XXX:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Encefalite equina venezuelana, virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus dell''encefalite equina venezuelana
nl-NL	Dutch (Netherlands)	Venezolaans equien encefalitisvirus As.neutraliserend:titer:moment:XXX:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam Venezolaans paardenencefalitisvirus
pl-PL	Polish (Poland)	Wirus wenezuelskiego końskiego zapalenia mózgu Ab.Neutralizujące:miano:punkt w czasie:XXX:półilościowy:test neutralizacji Synonyms: Przeciwciała do wirusa wenezuelskiego końskiego zapalenia mózgu Przeciwciała neutralizujące do wirusa wenezuelskiego końskiego zapalenia mózgu
zh-CN	Chinese (China)	委内端拉马脑脊髓炎病毒抗体.中和:滴定度:时间点:XXX:半定量型:中和试验 Synonyms: Ab;自身抗体 VEE 病毒 Ab VEE 病毒;VEEE;VEEV;囊膜病毒;外衣病毒;委内端拉马脑炎病毒 VEE 病毒抗体 VEEE Ab VEEE 抗体 VEEV Ab VEEV 抗体不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体似马的大脑炎委内端拉马脑炎病毒 Ab 委内端拉马脑炎病毒抗体委内端拉马脑脊髓炎病毒 Ab 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间脑炎（Encephalitis，大脑炎）脑脊髓炎脑脊髓炎（Encephalomyelitis）马的马科马科动物马科的

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.