Version 2.77

Part Descriptions

LP14237-9   Western equine encephalitis virus
Western equine encephalitis (WEE) is a relatively uncommon viral infection caused by the WEE virus, an Alphavirus of the family Togaviridae. WEE virus is an [arbovirus] (arthropod-borne virus) transmitted by mosquitoes of the genera Culex and Culiseta. There have been under 700 confirmed cases in the U.S. since 1964. In the U.S. WEE is seen mainly in states west of the Mississippi River. The disease is also seen in countries of South America. WEE is commonly a subclinical infection; symptomatic infections are uncommon. However, the disease can cause serious sequellae in infants and children. Unlike Eastern equine encephalitis, the overall mortality of WEE is low (approximately 4%) and is associated mostly with infection in the elderly. There is no vaccine for WEE and there are no licensed therapeutic drugs in the U.S. for this infection. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Western equine encephalitis virus (Wikipedia)

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Western equine encephalitis virus Ab.Neut
Property
Titr
Time
Pt
System
XXX
Scale
SemiQn
Method
Neut

Additional Names

Short Name
WEEV NAb Titr Spec Nt
Display Name
WEEV neut ab Neut test (Specimen) [Titer]
Consumer Name Alpha Get Info
WEEV neutralizing antibody, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.75
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32759-9 Western equine encephalitis virus

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Virus encefalitis equina del oeste Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:XXX:Semicuantitativo:Prueba de neutralización
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Virus de la encefalitis equina occidental Ab:Título:Punto temporal:XXX:Cuantitativo:Prueba de neutralización
fr-CA French (Canada) Virus de l'encéphalite équine de l'Ouest Ac.neut:Titre:Temps ponctuel:XXX:SemiQn:Test de neutralisation
fr-FR French (France) Encéphalite équine de l'ouest virus Ac:Titre:Ponctuel:Milieux divers:Semi-Quantitatif:Neutralisation
it-IT Italian (Italy) Encefalite equina occidentale, virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus dell''encefalite equina occidentale
nl-NL Dutch (Netherlands) Westers equien encefalitisvirus As.neutraliserend:titer:moment:XXX:semikwantitatief:neutralisatietest
Synonyms: antistof; antilichaam Westers paardenencefalitisvirus
pl-PL Polish (Poland) Wirus zachodniego zapalenia mózgu koni Ab.Neutralizujące:miano:punkt w czasie:XXX:półilościowy:test neutralizacji
Synonyms: Przeciwciała do wirusa zachodniego zapalenia mózgu koni Przeciwciała neutralizujące do wirusa zachodniego zapalenia mózgu koni Wirus zachodniego zapalenia mózgu koni
zh-CN Chinese (China) 西方马脑炎病毒 抗体.中和:滴定度:时间点:XXX:半定量型:中和试验
Synonyms: Ab;自身抗体 WEE 病毒 Ab WEE 病毒;WEEV;囊膜病毒;外衣病毒;西部马脑炎病毒 WEE 病毒抗体 WEEV Ab WEEV 抗体 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 似马的 大脑炎 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 脑炎（Encephalitis，大脑炎） 脑脊髓炎 脑脊髓炎（Encephalomyelitis） 西 西域 西域的 西方的 西方马脑炎病毒 Ab 西洋 西洋的 西部马脑炎病毒 Ab 西部马脑炎病毒抗体 马的 马科 马科动物 马科的

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95655-7