96121-9
SARS-related coronavirus E gene [Presence] in Lower respiratory specimen by NAA with probe detection
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Part Description
LP417600-6 SARS-related coronavirus E gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance]
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | Coronavirus (COVID-19) Testing |
| Mapping Guidance | LOINC | Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings. |
Fully-Specified Name
- Component
- SARS-related coronavirus E gene
- Property
- PrThr
- Time
- Pt
- System
- Respiratory system specimen.lower
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- SARS-rel CoV E gene Low resp Ql NAA+prb
- Display Name
- SARS-related coronavirus E gene NAA+probe Ql (Lower resp)
- Consumer Name Alpha Get Info
- SARS-related coronavirus E gene, Lower respiratory
Example Answer List: LL2021-5
Source: Gen-Probe| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) | LA15841-2 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.77
- Change Reason
- Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94393-6 | Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with probe detection |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG50982-4 | SARS-related coronavirus |
| LG51048-3 | SARS-related coronavirus E gene| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: SARS-CoV-2 E-Gen ql. /BAL PCR |
| de-DE | German (Germany) | SARS-bezogenes Coronavirus E-Gen: |
| es-MX | Spanish (Mexico) | Gen del coronavirus E relacionado con el SARS: |
| fr-FR | French (France) | Coronavirus SARS apparentés gène E: |
| nl-NL | Dutch (Netherlands) | SARS-gerelateerd coronavirus E-gen: Synonyms: onderste ademhalingsstelsel; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=96121-9
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright