Version 2.77

Part Description

LP420097-0   DOCK8 expression panel
Dedicator of cytokinesis 8 (DOCK8) protein plays a role in regulating the cellular cytoskeleton, particularly microfilaments. DOCK8 is important in immunity by contributing to cellular migration, cytotoxicity, antibody production, and immunological memory. Deficiency of DOCK8 causes an immunodeficiency that presents in childhood with features including recurrent sinopulmonary infections, cutaneous viral infection, Staphylococcus aureus skin infections, cancer, and atopic disease (due to hyperimmunoglobulin E). NK cells (CD45+CD14-CD3-CD56+), T cells (CD3+CD14-CD45+), B cells (CD3-CD14-CD19+CD45+), and monocytes (CD45+CD14+) are all expected to express the DOCK8 protein. Therefore, assessment of DOCK8 expression on immune cells facilitates the diagnosis of DOCK8 deficiency. PMID: 28625885 Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
96415-5 DOCK8 expression panel - Blood by Flow cytometry (FC)
Indent96416-3 Cells.CD3+CD14-CD45+DOCK8+/100 Cells.CD3+CD14-CD45+ in Blood by Flow cytometry (FC) %
Indent96417-1 Cells.CD3-CD14-CD19+CD45+DOCK8+/100 Cells.CD3-CD14-CD19+CD45+ in Blood by Flow cytometry (FC) %
Indent96418-9 Cells.CD3-CD14-CD45+CD56+DOCK8+/100 Cells.CD3-CD14-CD45+CD56+ in Blood by Flow cytometry (FC) %
Indent96419-7 Cells.CD3-CD14+CD45+DOCK8+/100 Cells.CD3-CD14+CD45+ in Blood by Flow cytometry (FC) %
Indent69052-9 Flow cytometry specialist review of results

Fully-Specified Name

Component
DOCK8 expression panel
Property
-
Time
Pt
System
Bld
Scale
-
Method
Flow cytometry

Additional Names

Short Name
DOCK8 Expr Pnl Bld FC
Display Name
DOCK8 expression panel FC (Bld)
Consumer Name Alpha Get Info
DOCK8 expression panel, Blood

Basic Attributes

Class
PANEL.CELLMARK
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de expresión DOCK8:Propiedades mixtas (sólo paneles):Punto temporal:Sangre:-:Citometria de flujo (FC)
es-MX Spanish (Mexico) Panel de expresión DOCK8:-:Punto temporal:Sangre:-:Citometría de flujo (FC)
fr-FR French (France) DOCK8 expression panel:-:Ponctuel:Sang:-:Cytométrie de flux
it-IT Italian (Italy) Espressione di DOCK8, panel:-:Pt:Sangue:-:Citometria a flusso
Synonyms: Citometria a flusso (FC) Modelli di superficie cellulare Punto nel tempo (episodio) Sangue Set di prescrizione per marcatore cellulare
nl-NL Dutch (Netherlands) DOCK8-expressie panel:-:moment:bloed:-:flowcytometrie
zh-CN Chinese (China) DOCK8 表达组套:-:时间点:全血:-:流式细胞测量术
Synonyms: DOCK8（胞质分裂作用因子 8）表达（基因表达）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;胞质分裂作用因子8;Dedicator of Cytokinesis number 8;DOCK8 动态 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.细胞标志物;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）类.细胞标志物;实验室医嘱组类.细胞标志物;细胞标志物医嘱组;细胞标志物医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 组 组合 组合医嘱 组合类 组套 细胞标志物 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96415-5
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/96415-5