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Part Descriptions

LP173592-9   Adalimumab
Adalimumab is a human monoclonal antibody that binds tumor necrosis factor alpha (TNFα). TNFα is a cell signaling protein that, when present in excess, may lead to the development of inflammatory immune diseases including Crohn's disease, rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. Adalimumab inactivates TNFα by binding to the TNFα receptor. PMID: 23943614 Treatment with adalimumab does not necessitate laboratory monitoring though association with increased transamines and pancytopenia may argue for intermittant blood cell counts and liver function tests. Adalimumab has been associated with serious infections including the reactivation of tuberculosis and deep fungal infections as well as other rare side effects, including lymphoma, heart failure and demyelinating disease. PMID: 16011443 Source: Regenstrief LOINC

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LOINC Names Get Info

Fully-Specified Name
Adalimumab^trough:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Adalimumab [Mass/volume] in Serum or Plasma --trough
Short Name
Adalimumab Trough SerPl-mCnc
Display Name
Adalimumab trough [Mass/Vol]
Consumer Name Alpha Get Info
Adalimumab trough, Blood

Part Model Get Info

  • Component
    Adalimumab^trough
    LP427308-4
    • Analyte
      Adalimumab
      LP173592-9
      • Component Numerator
        Adalimumab
        LP173592-9
        • Component Numerator Core
          Adalimumab
          LP173592-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      trough
      LP20176-1
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Adalimumab^Údolní koncentrace:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Αδαλιμουμάμπη^ελάχιστα επίπεδα:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn Αδαλιμουμάμπη ελάχιστα επίπεδα Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)Adalimumab^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Adalimumab^canal:MCnc:Punto temporal:Ser / Plas:Cuantitativo:
fr-FRFrench (France)Adalimumab^taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Adalimumab^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NLDutch (Netherlands)adalimumab^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
ru-RURussian (Russian Federation)Адалимумаб^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Adalimumab^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CNChinese (China)阿达木单抗^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: Adalimumab 单抗;人体抗肿瘤坏死因子-α单克隆抗体;阿达莫单抗;阿达木;阿达莫;阿达木单克隆抗体 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

UnitSource
ug/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97170-5