97235-6
Cocaine [Presence] in Cord tissue by Confirmatory method
Active
Part Descriptions
LP16048-8 Cocaine
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. PMID: 8761012
Source: Regenstrief LOINC
LP16048-8 Cocaine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Cocaine
- Property
- PrThr
- Time
- Pt
- System
- TissCo
- Scale
- Ord
- Method
- Confirm
Additional Names
- Short Name
- Cocaine TissCo Ql Cfm
- Display Name
- Cocaine Confirm Ql (Umb cord tissue)
- Consumer Name Alpha Get Info
- Cocaine, Umbilical cord tissue
Example Answer List: LL744-4
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.70
- Last Updated
- Version 2.70
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37611-7 | Cocaine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Cocaína: |
| es-ES | Spanish (Spain) | Cocaína: |
| fr-FR | French (France) | Cocaïne: |
| it-IT | Italian (Italy) | Cocaina: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) Tessuto del cordone ombelicale |
| nl-NL | Dutch (Netherlands) | cocaïne: |
| zh-CN | Chinese (China) | 可卡因: Synonyms: C17H21NO4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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