Version 2.70

97748-8Cytokeratin 19 [Mass/volume] in AspirateActive

Part Descriptions

LP19423-0   Cytokeratin 19
Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a protein that in humans is encoded by the KRT19 gene.

Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Depending on the assays, KRT19 has been shown to be both a specific and a non-specific marker. False positivity in such KRT19 RT-PCR studies include: illegitimate transcription (expression of small amounts of KRT19 mRNA by tissues in which it has no real physiological role), haematological disorders (KRT19 induction in peripheral blood cells by cytokines and growth factors, which circulate at higher concentrations in inflammatory conditions and neutropenia), the presence of pseudogenes (two KRT19 pseudogenes, KRT19a and KRT19b, have been identified, which have significant sequence homology to KRT19 mRNA. Subsequently, attempts to detect the expression of the authentic KRT19 may result in the detection of either or both of these pseudogenes), sample contamination (introduction of contaminating epithelial cells during peripheral blood sampling for subsequent RT-PCR analysis).

Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP7037-7   Asp
In LOINC, the System "Asp" represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" should not be used to represent named body fluids, such as synovial fluid or peritoneal fluid, because those fluids are not inherently pathologic and also, they have their own named Systems in LOINC. Source: Regenstrief LOINC

Fully-Specified Name

Cytokeratin 19

Additional Names

Short Name
CK 19 Aspirate-mCnc
Display Name
Cytokeratin 19 (Asp) [Mass/Vol]
Consumer Name Alpha
Cytokeratin 19, Aspirate

Basic Attributes

First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
细胞角蛋白 19:质量浓度:时间点:吸出物:定量型:
nl-NLDutch (Netherlands)
cytokeratine 19:massa/volume:moment:aspiraat:kwantitatief:
et-EEEstonian (Estonia)
Tsütokeratiin 19:MCnc:Pt:Asp:Qn:
fr-BEFrench (Belgium)
Cytokératine 19:Concentration de masse:Temps ponctuel:Aspirat:Quantitatif:
fr-CAFrench (Canada)
Cytokératine 19:Concentration de masse:Temps ponctuel:Aspirat:Quantitatif:
it-ITItalian (Italy)
Citocheratina 19:MCnc:Pt:Aspirato:Qn:
ru-RURussian (Russian Federation)
Цитокератин 19:МассКонц:ТчкВрм:Асп:Колич:
es-ESSpanish (Spain)
Citoqueratina 19:Concentración de masa:Punto temporal:Asp:Qn:
tr-TRTurkish (Turkey)
Sitokeratin 19:KütlKons:Zmlı:Asp:Kant:

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info