LOINC
Version 2.70

97934-4Toscana virus RNA [Presence] in Specimen by NAA with probe detectionActive

Part Descriptions

LP190786-6   Toscana virus
Toscana virus (TOSV) was identified in 1971 in central Italy from sandflies Phlebotomus perniciosus and Phlebotomus perfiliewi [PMID: 24175218] . TOSV belongs to the family Phenuiviridae, genus Phlebovirus [NCBI: 11590)]. TOSV is a serotype of the species Sandfly fever Naples virus [PMID: 24175218] . TOSV is the only neurotropic sandfly phlebovirus typically causing meningitis and encephalitis. Additional neuroinvasive manifestations such as Guillain-Barré syndrome, hydrocephalus, myositis, fasciitis, polymyeloradiculopathy, deafness, and facial paralysis, have been reported. Toscana virus broadly circulates in in European Mediterranean basin and Northern Africa [PMID: 32878929] . Source: Regenstrief LOINC

LP190786-6   Toscana virus
The Toscana virus (TOSV) belongs to the Bunyaviridae family whose genome is made of three negative single-stranded RNA segments. There are two genotypes of TOSV: A, found mainly in Italy, and B, occurring mainly in Spain. The distribution of the two genotypes may indicate the involvement of different vectors. Infection by TOSV is most prevalent in Italy and Spain in the summer months, though the geographical region where TOSV is expanding includes other countries in the Mediterranean basin. TOSV is transmitted to humans by the Phlebotomus species of sandflies. Though the animal reservoir has not been identified, TOSV has been isolated from the brain of a bat, which raises the question of it possibly being a host to the virus. TOSV causes aseptic meningitis in 95% of the people it infects, meningoencephalitis in 4.5% of those infected, and an influenza-like illness in the remaining .5% who are infected. Recently, unusual symptoms associated with TOSV have included ischemic complications and hydrocephalus. TOSV is emerging as an important pathogen as its distribution increases due to changes in the climate, globalization and habitat modification. Other than supportive therapy, there is no treatment for infection with TOSV. [PMID: 20517492] Source: Regenstrief LOINC

Fully-Specified Name

Component
Toscana virus RNA
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
TOSV RNA Spec Ql NAA+probe
Display Name
Toscana virus RNA NAA+probe Ql (Specimen)
Consumer Name Alpha
Toscana virus, Specimen

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
托斯卡纳病毒 RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
Toscana virus RNA:aanwezigheid:moment:XXX:ordinaal:moleculaire techniek (PCR)
it-ITItalian (Italy)
Virus Toscana RNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar
es-ESSpanish (Spain)
Virus Toscana RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
tr-TRTurkish (Turkey)
Toscana virüs RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97934-4