97966-6

European house dust mite recombinant (rDer p) 2 IgG4 Ab [Mass/volume] in Serum

Active

Part Descriptions

LP113781-1 Dermatophagoides pteronyssinus recombinant (rDer p) 2
Dermatophagoides pteronyssinus Der p 1 and Der p 2 can be used for selecting patients for specific immunotherapy (SIT). Specific IgE antibodies to Der p 1 and Der p 2 indicates that the patient is a suitable candidate for SIT to house dust mite. Der p 1 and Der p 2 complement the extract based allergens d1 d2, in providing a more detailed sensitization profile of mite allergic patients. Copyright Copyright © 2006 Phadia AB. Source: ImmunoCap, ImmunoCap

LP113781-1 Dermatophagoides pteronyssinus recombinant (rDer p) 2
Dermatophagoides pteronyssinus is one of thirteen species of dust mites that are found in temperate climates worldwide, and is a major source of mite allergen. The three most common dust mites include Dermatophagoides farinae, Dermatophagoides pteronyssinus and Euroglyphus maynei. Dust mites feed on skin scales and other organic debris. Their feces and bodies are the source of many of the allergens that affect humans. House dust mite allergens are divided into 13 groups that are based on their biochemical structure, sequence homology, and molecular weight. Each allergen is designated by the first three letters of the genus of house mite with which it is associated, then the first letter of the species name, and finally a number that indicates the order in which the allergen was isolated. Group 1 allergens are glycoproteins that originally lined the intestinal tract of the mite and possess cysteine protease activity. The epitope Der p 1 increases allergenicity by its ability to split both the CD23 IgE receptor found on the membrane of human B cells, and the CD25 subunit of the T-cell IL-2 receptor. PMID: 11242601 Source: Regenstrief LOINC

LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Dermatophagoides pteronyssinus recombinant (rDer p) 2 Ab.IgG4:MCnc:Pt:Ser:Qn:
Long Common Name: European house dust mite recombinant (rDer p) 2 IgG4 Ab [Mass/volume] in Serum
Short Name: D pteronyss (rDer p) 2 IgG4-mCnc
Display Name: European house dust mite recombinant (rDer p) 2 IgG4 (S) [Mass/Vol]
Consumer Name Alpha Get Info: European house dust mite recombinant (rDer p) 2 IgG4 antibody

Part Model Get Info

Component
Dermatophagoides pteronyssinus recombinant (rDer p) 2 Ab.IgG4
LP427261-5
- Analyte
  Dermatophagoides pteronyssinus recombinant (rDer p) 2 Ab.IgG4
  LP427261-5
  - Component Numerator
    Dermatophagoides pteronyssinus recombinant (rDer p) 2 Ab.IgG4
    LP427261-5
    - Component Numerator Core
      Dermatophagoides pteronyssinus recombinant (rDer p) 2
      LP113781-1
    - Component Numerator Core Suffix
      Ab.IgG4
      LP32397-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: ALLERGY
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.70 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Dermatophagoides pteronyssinus rekombinantní (rDer p) 2 Ab.IgG4:Hmotnostní koncentrace:Časový bod:Sérum:Kvantitativní:
el-GR	Greek (Greece)	Ανασυνδυασμένο Dermatophagoides pteronyssinus (Ακάρεα σκόνης) (rDer p) 2 Ab.IgG4:MCnc:Pt:Ορός:Qn: Synonyms: Ab.IgG4 ALLERGY Dermatophagoides pteronyssinus (Ακάρεα σκόνης) MCnc P Pt Qn Ανασυνδυασμένο Dermatophagoides pteronyssinus (Ακάρεα σκόνης) (rDer p) 2 Αντίσωμα Ορός
es-ES	Spanish (Spain)	Dermatophagoides pteronyssinus recombinante (rDer p) 2 IgG4:Concentración de masa:Punto temporal:Suero:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Dermatophagoides pteronyssinus recombinante (rDer p) 2 Ab.IgG4:MCnc:Punto temporal:Suero:Cuantitativo:
fr-CA	French (Canada)	Dermatophagoides pteronyssinus rDer p2 (recombinant), IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-FR	French (France)	Dermatophagoides pteronyssinus rDer p2 (recombinant) Ac IgG4:Masse/Volume:Ponctuel:Sérum:Numérique:
it-IT	Italian (Italy)	Dermatophagoides pteronyssinus, ricombinante (nDer p) 2 Ab.IgG4:MCnc:Pt:Siero:Qn: Synonyms: Anticorpi IgG4 anticorpo Concentrazione di Massa Punto nel tempo (episodio) Ricombinante (rDer p) 2 di Dermatophagoides pteron Risposta agli antigeni Siero
nl-NL	Dutch (Netherlands)	Dermatophagoides pteronyssinus recombinant (rDer p) 2 As.IgG4:massa/volume:moment:serum:kwantitatief: Synonyms: antistof; antilichaam Europese huisstofmijt
pl-PL	Polish (Poland)	Dermatophagoides pteronyssinus rekombinowana komponenta alergenowa (rDer p) 2 Ab.IgG4:stężenie masowe:punkt w czasie:surowica:ilościowy: Synonyms: Rekombinowana komponenta alergenowa (rDer p) 2 skórożarłoczka skrytego (Dermatophagoides pteronyssinus);Rekombinowana komponenta alergenowa (rDer p) 2 Roztocza kurzu domowego (Dermatophagoides pteronyssinus) Roztocze kurzu domowego;Skórożarłoczek skryty
ru-RU	Russian (Russian Federation)	Dermatophagoides pteronyssinus нативный (nDer p) 2 Ат.IgG4:МассКонц:ТчкВрм:Сыв:Колич: Synonyms: Антитело Количественный Массовая концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Dermatophagoides pteronyssinus native (nDer p) 1 Ab.IgG4:KütlKons:Zmlı:Ser:Kant: Synonyms: Ak Ak.IgG4
zh-CN	Chinese (China)	屋尘螨重组 (rDer p) 2 抗体.IgG4:质量浓度:时间点:血清:定量型: Synonyms: Ⅱ Ab.IgG4;IgG4;抗体 IgG4 Ab;自身抗体 II P 型可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积)

Example Units

Unit	Source
mg/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.