LOINC
Version 2.70

97973-2Peanut recombinant (rAra h) 1 IgG4 Ab [Mass/volume] in SerumActive

Part Descriptions

LP99507-3   Arachis hypogaea recombinant (rAra h) 1
Recombinant non-glycosylated protein produced in an E. coli strain carrying a cloned cDNA encoding Arachis hypogaea allergen Ara h 1, Ara h 2 or Ara h 3.

Ara h 1 comprises 12% to 16% of the total protein in Peanut in population studies, sensitisation to Ara h 1 was found in 95% of Peanut-allergic patients from North America , but in fewer Peanut-allergic patients of 3 European populations, varying from 35% to 70% . These differences were not reported for Ara h 2, even though Peanuts from different varieties and from different parts of the world contain similar proteins and the IgE binding properties are similar. Unidentified Peanut proteins with molecular weights somewhat lower than 15 kDa may be important allergens as well. Ara h 3 is recognised by serum IgE from 45% - 50% of patients with Peanut sensitivity. Copyright Copyright © 2006 Phadia AB. Source: ImmunoCap, ImmunoCap

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a “blocking” antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID: 26023323] . IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Component
Arachis hypogaea recombinant (rAra h) 1 Ab.IgG4
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Peanut (rAra h) 1 IgG4-mCnc
Display Name
Peanut recombinant (rAra h) 1 IgG4 (S) [Mass/Vol]
Consumer Name Alpha
Peanut recombinant (rAra h) 1 IgG4 antibody

Basic Attributes

Class
ALLERGY
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
落花生 重组 (rAra h) 1 抗体.IgG4:质量浓度:时间点:血清:定量型:
nl-NLDutch (Netherlands)
Arachis hypogaea recombinant (rAra h) 1 As.IgG4:massa/volume:moment:serum:kwantitatief:
fr-BEFrench (Belgium)
Arachide (Arachis hypogaea) recombinant (rAra h) 1 Anticorps. IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-CAFrench (Canada)
Arachide (Arachis hypogaea) recombinant (rAra h) 1 , IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
it-ITItalian (Italy)
Arachis hypogaea, ricombinante (rAra h) 1 , Ab.IgG4:MCnc:Pt:Siero:Qn:
ru-RURussian (Russian Federation)
Arachis hypogaea рекомбинантный (rAra h) 1 Ат.IgG4:МассКонц:ТчкВрм:Сыв:Колич:
es-ESSpanish (Spain)
Arachis hypogaea recombinante (rAra h) 1 IgG4:Concentración de masa:Punto temporal:Suero:Qn:
tr-TRTurkish (Turkey)
Arachis hypogaea rekombinant (rAra h) 1 Ab.IgG4:KütlKons:Zmlı:Ser:Kant:

Example Units

Unit Source
mg/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97973-2