97973-2
Peanut recombinant (rAra h) 1 IgG4 Ab [Mass/volume] in Serum
Active
Part Descriptions
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease
Source: Regenstrief LOINC
LP99507-3 Arachis hypogaea recombinant (rAra h) 1
Recombinant non-glycosylated protein produced in an E. coli strain carrying a cloned cDNA encoding Arachis hypogaea allergen Ara h 1, Ara h 2 or Ara h 3.
Ara h 1 comprises 12% to 16% of the total protein in Peanut in population studies, sensitisation to Ara h 1 was found in 95% of Peanut-allergic patients from North America , but in fewer Peanut-allergic patients of 3 European populations, varying from 35% to 70% . These differences were not reported for Ara h 2, even though Peanuts from different varieties and from different parts of the world contain similar proteins and the IgE binding properties are similar. Unidentified Peanut proteins with molecular weights somewhat lower than 15 kDa may be important allergens as well. Ara h 3 is recognised by serum IgE from 45% - 50% of patients with Peanut sensitivity.
Copyright Copyright © 2006 Phadia AB.
Source: ImmunoCap,
ImmunoCap
LOINC Names Get Info
- Fully-Specified Name
- Arachis hypogaea recombinant (rAra h) 1 Ab.IgG4:
MCnc: Pt: Ser: Qn: - Long Common Name
- Peanut recombinant (rAra h) 1 IgG4 Ab [Mass/volume] in Serum
- Short Name
- Peanut (rAra h) 1 IgG4-mCnc
- Display Name
- Peanut recombinant (rAra h) 1 IgG4 (S) [Mass/Vol]
- Consumer Name Alpha Get Info
- Peanut recombinant (rAra h) 1 IgG4 antibody
Part Model Get Info
- Component
- Arachis hypogaea recombinant (rAra h) 1 Ab.IgG4
LP427248-2
- Analyte
- Arachis hypogaea recombinant (rAra h) 1 Ab.IgG4
LP427248-2
- Component Numerator
- Arachis hypogaea recombinant (rAra h) 1 Ab.IgG4
LP427248-2
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- MCnc
LP6827-2
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- ALLERGY
- Type
- Laboratory
- First Released
- Version 2.70
- Last Updated
- Version 2.70 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Arachis hypogaea rekombinantní (rAra h) 1 Ab.IgG4: |
| el-GR | Greek (Greece) | Ανασυνδυασμένο Arachis hypogaea (Φυστίκι αράπικο) (rAra h) 1 Ab.IgG4: Synonyms: Ab.IgG4 ALLERGY Arachis hypogaea (Φυστίκι αράπικο) H MCnc Pt Qn Ανασυνδυασμένο Arachis hypogaea (Φυστίκι αράπικο) (rAra h) 1 Αντίσωμα Ορός |
| es-ES | Spanish (Spain) | Arachis hypogaea recombinante (rAra h) 1 IgG4: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Arachis hypogaea recombinante (rAra h) 1 Ab.IgG4: |
| fr-BE | French (Belgium) | Arachide (Arachis hypogaea) recombinant (rAra h) 1 Anticorps. IgG4: Synonyms: Anticorps Arachide,f13 f422 |
| fr-CA | French (Canada) | Arachide (Arachis hypogaea) recombinant (rAra h) 1, IgG4: |
| fr-FR | French (France) | Arachide rAra h1 (recombinant) Ac IgG4: |
| it-IT | Italian (Italy) | Arachis hypogaea, ricombinante (rAra h) 1 Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Arachide (Arachis hypogaea) Concentrazione di Massa Punto nel tempo (episodio) Ricombinante (rAra h) 1 di arachide (Arachis hypog Risposta agli antigeni Siero |
| nl-NL | Dutch (Netherlands) | Arachis hypogaea recombinant (rAra h) 1 As.IgG4: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Arachis hypogaea rekombinowany (rAra h) 1 Ab.IgG4: Synonyms: Komponenta alergenowa Ara h 1 orzecha ziemnego (Arachis hypogaea) Orzeszek ziemny; |
| ru-RU | Russian (Russian Federation) | Arachis hypogaea рекомбинантный (rAra h) 1 Ат.IgG4: Synonyms: Антитело Арахис (Arachis hypogaea) рекомбинантный (rAra h) 1 Арахис культурный (Arachis hypogaea) Количественный Массовая концентрация Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Arachis hypogaea rekombinant (rAra h) 1 Ab.IgG4: Synonyms: Ak Ak.IgG4 |
| zh-CN | Chinese (China) | 落花生 重组 (rAra h) 1 抗体.IgG4: Synonyms: Ⅰ Ab.IgG4; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://