Version 2.78

Part Description

LP428361-2   CD154 function (binding to CD40)
CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF family of molecules. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In general, CD40L plays the role of a costimulatory molecule and induces activation in APC in association with T cell receptor stimulation by MHC molecules on the APC. The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene, which could result in either reduced expression or normal expression with reduced functional binding to CD40, results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD154

Fully-Specified Name

Component
CD154 function (binding to CD40)
Property
PrThr
Time
Pt
System
T cells
Scale
Ord
Method

Additional Names

Short Name
CD154 Function T cells Ql
Display Name
CD154 function (binding to CD40) Ql (T cells)
Consumer Name Alpha Get Info
CD154 function (binding to CD40), T cells

Example Answer List: LL1937-3

Source: 3M Health Information Systems
Answer Code Score Answer ID
PresentCopyright http://snomed.info/sct ID:52101004 Present (qualifier value) LA9633-4
AbsentCopyright http://snomed.info/sct ID:2667000 Absent (qualifier value) LA9634-2

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.71
Last Updated
Version 2.71
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
98239-7 CD154 expression and function panel - T cells by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Función de CD154 (unión a CD40):PrThr:Punto temporal:Células T:Ord:
fr-FR French (France) CD154 fonction (lié au CD40):Présence/Seuil:Ponctuel:Lymphocytes T:Qualitatif:
it-IT Italian (Italy) CD154 funzione (legante a CD40):PrThr:Pt:Cellule T:Ord:
Synonyms: Modelli di superficie cellulare Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) CD154-functie (binden aan CD40):aanwezigheid:moment:T-cellen:ordinaal:
zh-CN Chinese (China) CD154 功能 (结合 CD40):存在情况或阈值:时间点:T 细胞:序数型:
Synonyms: Bp50 FCN T-细胞 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 细胞标志物 结合性 结合性的

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=98241-3