Version 2.78

Term Description

Osmotic fragility tests are used to help diagnose various types of spherocytosis, including hereditary spherocytosis and some types of congenital hemolytic anemias.
Source: Regenstrief LOINC

Part Description

LP426982-7   Osmotic fragility panel
Hemolytic anemia can be caused by red blood cell (RBC) membrane disorders such as hereditary spherocytosis, hereditary pyropoikilocytosis, hereditary elliptocytosis, and hereditary stomatocytosis. Alterations in the RBC membrane cause its shape to change from the typical torus, resulting in a lower surface area that makes the cell more fragile when placed in a hypotonic saline solution. This fragility becomes greater over time, as RBC membrane changes faster than normal. Osmotic fragility testing evaluates the extent of RBC membrane alteration. PMID: 24237975 Source: LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
98904-6 Osmotic fragility panel of Red Blood Cells
Indent4667-2 Osmotic fragility of Red Blood Cells %
Indent40739-5 Osmotic fragility of Red Blood Cells--unincubated %
Indent40740-3 Osmotic fragility of Red Blood Cells--Incubated %
Indent50794-7 Osmotic fragility beginning hemolysis of Red Blood Cells %
Indent50795-4 Osmotic fragility full hemolysis of Red Blood Cells %
Indent23910-3 Osmotic fragility of Red Blood Cells--0.0% sodium chloride %
Indent31103-5 Osmotic fragility of Red Blood Cells--0.0% sodium chloride 24 hour 37 degree C incubation %
Indent34966-2 Osmotic fragility of Red Blood Cells--0.10% sodium chloride %
Indent34965-4 Osmotic fragility of Red Blood Cells--0.10% sodium chloride 24 hour 37 degree C incubation %
Indent34968-8 Osmotic fragility of Red Blood Cells--0.20% sodium chloride %
Indent34967-0 Osmotic fragility of Red Blood Cells--0.20% sodium chloride 24 hour 37 degree C incubation %
Indent23911-1 Osmotic fragility of Red Blood Cells--0.30% sodium chloride %
Indent31110-0 Osmotic fragility of Red Blood Cells--0.30% sodium chloride 24 hour 37 degree C incubation %
Indent23912-9 Osmotic fragility of Red Blood Cells--0.35% sodium chloride %
Indent31109-2 Osmotic fragility of Red Blood Cells--0.35% sodium chloride 24 hour 37 degree C incubation %
Indent23913-7 Osmotic fragility of Red Blood Cells--0.40% sodium chloride %
Indent31108-4 Osmotic fragility of Red Blood Cells--0.40% sodium chloride 24 hour 37 degree C incubation %
Indent23914-5 Osmotic fragility of Red Blood Cells--0.45% sodium chloride %
Indent31107-6 Osmotic fragility of Red Blood Cells--0.45% sodium chloride 24 hour 37 degree C incubation %
Indent23915-2 Osmotic fragility of Red Blood Cells--0.50% sodium chloride %{hemolysis};%
Indent31106-8 Osmotic fragility of Red Blood Cells--0.50% sodium chloride 24 hour 37 degree C incubation %
Indent23916-0 Osmotic fragility of Red Blood Cells--0.55% sodium chloride %
Indent31105-0 Osmotic fragility of Red Blood Cells--0.55% sodium chloride 24 hour 37 degree C incubation %
Indent23917-8 Osmotic fragility of Red Blood Cells--0.60% sodium chloride %{hemolysis};%
Indent23918-6 Osmotic fragility of Red Blood Cells--0.60% sodium chloride 24 hour 37 degree C incubation %
Indent23919-4 Osmotic fragility of Red Blood Cells--0.65% sodium chloride %{hemolysis};%
Indent23920-2 Osmotic fragility of Red Blood Cells--0.65% sodium chloride 24 hour 37 degree C incubation %
Indent30543-3 Osmotic fragility of Red Blood Cells--0.75% sodium chloride %{hemolysis};%
Indent23921-0 Osmotic fragility of Red Blood Cells--0.75% sodium chloride 24 hour 37 degree C incubation %
Indent23922-8 Osmotic fragility of Red Blood Cells--0.85% sodium chloride %
Indent31104-3 Osmotic fragility of Red Blood Cells--0.85% sodium chloride 24 hour 37 degree C incubation %
Indent52124-5 Osmotic fragility of Red Blood Cells--0.90% sodium chloride %
Indent52125-2 Osmotic fragility of Red Blood Cells--0.90% sodium chloride 24 hour 37 degree C incubation %
Indent96045-0 Osmotic fragility of Red Blood Cells--10% glucose 48 hour 37 degree C incubation %
Indent34964-7 Osmotic fragility [Interpretation] of Red Blood Cells
Indent32862-5 Osmotic fragility [Interpretation] of Red Blood Cells--Incubated
Indent40432-7 Osmotic fragility [Interpretation] of Red Blood Cells from Control--Incubated
Indent32863-3 Osmotic fragility [Interpretation] of Red Blood Cells--fresh
Indent40431-9 Osmotic fragility [Interpretation] of Red Blood Cells from Control--fresh

Fully-Specified Name

Component
Osmotic fragility panel
Property
-
Time
Pt
System
RBC
Scale
-
Method

Additional Names

Short Name
OF Pnl RBC
Display Name
Osmotic fragility panel (RBC)
Consumer Name Alpha Get Info
Osmotic fragility panel, Red blood cells

Basic Attributes

Class
PANEL.HEM/BC
Type
Laboratory
First Released
Version 2.72
Last Updated
Version 2.72
Order vs. Observation
Order
Panel Type
Panel

Member of these Panels

LOINC Long Common Name
98903-8 Hemolytic anemia panel
98905-3 Red blood cell membrane evaluation panel - Red Blood Cells

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de fragilidad osmótica:Propiedades mixtas (sólo paneles):Punto temporal:Glóbulos rojos:-:
fr-FR French (France) Fragilité osmotique panel:-:Ponctuel:Érythrocytes:-:
it-IT Italian (Italy) Fragilità osmotica, panel:-:Pt:RBC:-:
Synonyms: Ematologia (coagulazione) conta differenziale Globuli rossi Panel di fragilità osmotica Punto nel tempo (episodio) Set di prescrizione per ematologia e conta del san
zh-CN Chinese (China) 渗透脆性组套:-:时间点:红细胞:-:
Synonyms: OF Osmo RBC;RBCS;红血球;红血细胞;赤血球 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.血液学/细胞计数;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.血液学与细胞计数;医嘱组类.血液学/细胞计数;医嘱组类.血液学与细胞计数;实验室医嘱组类.血液学与细胞计数;血液学与细胞计数医嘱组;血液学与细胞计数医嘱组类;实验室医嘱组类.血液学/细胞计数 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 渗透性 渗透性的 渗透的 渗透的（Osmotic，Osmo） 渗透脆性（OF）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 组 组合 组合医嘱 组合类 组套 血液学/细胞计数;血液学与细胞计数

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=98904-6
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/98904-6