99115-8
Onyong-nyong virus neutralizing antibody [Titer] in Specimen by Neutralization test
Active
Part Descriptions
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP421093-8 Onyong-nyong virus
O'nyong-nyong virus (ONNV) was isolated in 1959 in Gulu, Uganda. Following the discovery ONNV has been responsible for several outbreaks in humans that occurred in East Africa. ONNV belongs in the family Togaviridae, genus Alphavirus [NCBI Taxonomy: 2169701]. ONNV is a mosquito-borne arthritogenic alphavirus PMID: 32477364. Vectors include Anopheles funestus and A. gambiae. ONNV produces symptoms of fever, headache, joint pains, and rash PMID: 16965706 .
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Onyong-nyong virus Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- XXX
- Scale
- SemiQn
- Method
- Neut
Additional Names
- Short Name
- ONN virus NAb Titr Spec Nt
- Display Name
- Onyong-nyong virus neut ab Neut test (Specimen) [Titer]
- Consumer Name Alpha Get Info
- Onyong-nyong virus neutralizing antibody, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Virus Onyong-nyong Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
fr-FR | French (France) | Onyong-nyong virus Ac neutralisant: |
it-IT | Italian (Italy) | Onyong-nyong, virus Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo |
nl-NL | Dutch (Netherlands) | Onyong-nyong-virus As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Onyong-nyong wirus Ab.Neutralizujące: Synonyms: Przeciwciała neutralizujące do wirusa Onyong-nyong Wirus Onyong-nyong |
zh-CN | Chinese (China) | 阿尼昂尼昂病毒 抗体.中和: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=99115-8
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright