99121-6

Rift valley fever virus neutralizing antibody [Titer] in Specimen by Neutralization test

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Part Descriptions

LP19936-1 Rift valley fever virus
Rift Valley Fever (RVF) is a viral zoonosis (affects primarily domestic livestock, but can be passed to humans) causing fever. It is spread by the bite of infected mosquitoes. The disease is caused by the RVF virus, a member of the genus Phlebovirus (family Bunyaviridae). The disease was first reported among livestock in Kenya around 1915, but the virus was not isolated until 1931. RVF outbreaks occur across sub-Saharan Africa, with outbreaks occurring elsewhere infrequently (but sometimes severely - in Egypt in 1977 -78, several million people were infected and thousands died during a violent epidemic; in September 2000 an outbreak was confirmed in Saudi Arabia and Yemen). In humans the virus can cause several different syndromes. Usually sufferers have either no symptoms or only a mild illness with fever, headache, myalgia and liver abnormalities. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Rift valley fever virus (Wikipedia)

LP19936-1 Rift valley fever virus
A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans. Source: National Library of Medicine, MeSH 2006

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Rift Valley fever virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut
Long Common Name: Rift valley fever virus neutralizing antibody [Titer] in Specimen by Neutralization test
Short Name: RVFV NAb Titr Spec Nt
Display Name: Rift valley fever virus neut ab Neut test (Specimen) [Titer]
Consumer Name Alpha Get Info: Rift Valley Fever virus neutralizing antibody, Specimen

Part Model Get Info

Component
Rift valley fever virus Ab.Neut
LP430463-2
- Analyte
  Rift valley fever virus Ab.Neut
  LP430463-2
  - Component Numerator
    Rift valley fever virus Ab.Neut
    LP430463-2
    - Component Numerator Core
      Rift valley fever virus
      LP19936-1
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.72
Last Updated: Version 2.75 (MAJ)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus horečky Rift Valley Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:XXX:Semikvantitativní:Neutralizační test
de-DE	German (Germany)	Rift-Valley-Fieber-Virus Ak.neutralisierend:Titer:Zeitpunkt:XXX:Semiquantitativ:Neutralisationstest Synonyms: RVFV
el-GR	Greek (Greece)	Ιός του πυρετού της κοιλίαδας Rift valley Ab.Neut:Titr:Pt:XXX:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr XXX Αντίσωμα Ημιποσοτική Ιός Ιός του πυρετού της κοιλίαδας Rift valley Ουδετερόφιλα Πυρετός
es-ES	Spanish (Spain)	Virus de la fiebre del valle del Rift Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:XXX:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
fr-FR	French (France)	Fièvre de la vallée du rift virus Ac neutralisant:Titre:Ponctuel:Milieux divers:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Virus fièvre Vallée du Rift Ac.neut:Titre:Temps ponctuel:XXX:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Febbre della valle del Rift, virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus della febbre della valle del Rift
nl-NL	Dutch (Netherlands)	Riftdalkoortsvirus As.neutraliserend:titer:moment:XXX:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus gorączki Doliny Rift Ab.Neutralizujące:miano:punkt w czasie:XXX:półilościowy:test neutralizacji Synonyms: Przeciwciała do wirusa gorączki Doliny Rift Przeciwciała neutralizujące do wirusa gorączki Doliny Rift Wirus RVF
zh-CN	Chinese (China)	裂谷热病毒抗体.中和:滴定度:时间点:XXX:半定量型:中和试验 Synonyms: Ab;自身抗体 Bunyavirus;RVF;RVFV;布尼亚病毒;布尼亚病毒属;布尼安病毒;布尼安病毒属;布尼病毒;布尼病毒属;立夫特谷热;立夫特谷热病毒;裂谷热;裂谷热（Rift valley fever，RVF） RVFV Ab RVFV 抗体不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体发烧;热病微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间立夫特谷热病毒 Ab 立夫特谷热病毒抗体裂谷热病毒 Ab

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.