99123-2
Heartland banyangvirus neutralizing antibody [Titer] in Specimen by Neutralization test
Active
Part Descriptions
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP417295-5 Heartland banyangvirus
Heartland banyangvirus, or Heartland virus (HRTV), is part of the genus Phlebovirus and can be transmitted by ticks, mosquitoes, and sandflies. Clinical symptoms of Heartland virus disease are similar to other tick-borne illness and include fever, fatigue, anorexia, headaches, nausea, diarrhea, and joint pain. Lab studies show leukopenia, thrombocytopenia, and elevation of liver transaminases. Testing for HRTV includes detection of Heartland virus RNA and IgM and IgG antibodies in various specimens, including CSF, whole blood, and serum. [CDC: heartland-virus]
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Heartland banyangvirus Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- XXX
- Scale
- SemiQn
- Method
- Neut
Additional Names
- Long Common Name
- Heartland banyangvirus neutralizing antibody [Titer] in Specimen by Neutralization test
- Short Name
- HRTV NAb Titr Spec Nt
- Display Name
- Heartland banyangvirus neut ab Neut test (Specimen) [Titer]
- Consumer Name Alpha Get Info
- Heartland banyangvirus neutralizing antibody, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.75 (MAJ)
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Ιός heartland banyangvirus Ab.Neut: Synonyms: Titr Ιός heartland banyangvirus |
es-ES | Spanish (Spain) | Bandavirus Heartland Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
fr-FR | French (France) | Heartland banyangvirus Ac neutralisant: |
it-IT | Italian (Italy) | Banyangvirus di Heartland Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo |
nl-NL | Dutch (Netherlands) | 'Heartland'-virus As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus heartland Ab.Neutralizujące: Synonyms: Przeciwciała neutralizujące do wirusa heartland Wirus heartland |
zh-CN | Chinese (China) | 心地班阳病毒 抗体.中和: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=99123-2
LOINC Copyright
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