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Part Description

LP16098-3   cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653 Source: Regenstrief LOINC, PMID: 19545653

LOINC Names Get Info

Fully-Specified Name
cycloSPORINE:TmMCnc:Pt:Bld:Qn:
Long Common Name
cycloSPORINE [AUC] in Blood
Short Name
cycloSPORINE Bld-AUC
Display Name
cycloSPORINE (Bld) [AUC]
Consumer Name Alpha Get Info
cycloSPORINE, Blood

Part Model Get Info

  • Component
    cycloSPORINE
    LP16098-3
    • Analyte
      cycloSPORINE
      LP16098-3
      • Component Numerator
        cycloSPORINE
        LP16098-3
        • Component Numerator Core
          cycloSPORINE
          LP16098-3
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    TmMCnc
    LP343621-1
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.72
Last Updated
Version 2.72 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Cyklosporin:Plocha pod křivkou (hmotnostní koncentrace):Časový bod:Krev:Kvantitativní:
el-GRGreek (Greece)Κυκλοσπορίνη:TmMCnc:Pt:Αίμα:Qn:
Synonyms: DRUG/TOX Pt Qn TmMCnc Αίμα Κυκλοσπορίνη
es-ESSpanish (Spain)Ciclosporina:Área bajo la curva:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
fr-CAFrench (Canada)Cyclosporine:Concentration de masse temporelle:Temps ponctuel:Sang:Quantitatif:
fr-FRFrench (France)Ciclosporine:Temps*Masse/Volume:Ponctuel:Sang:Numérique:
it-ITItalian (Italy)Ciclosporina:TmMCnc:Pt:Sangue:Qn:
Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
pl-PLPolish (Poland)Cyklosporyna:pole pod krzywą:punkt w czasie:krew:ilościowy:
zh-CNChinese (China)环孢菌素:曲线下面积:时间点:全血:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 曲线下的面积;曲线面积;Area under the curve;TmMCnc 毒品 毒品类 环孢霉素A; 山地明环孢灵; 环孢多肽A; 环孢素; 赛斯平; 环孢菌素; 环孢菌素A; 环孢素A;山地明;环孢多肽;环孢抑制剂;环孢灵;环孢霉素;环孢霉素A;环孢素;Cyclosporine;Cyclosporin; Restasis; Cyclosporine A; cyclosporin A; Antibiotic S 7481F1; 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonameth 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

UnitSource
ug.h/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=99413-7