99452-5

Silver Birch recombinant (rBet v) 2 IgG4 Ab [Mass/volume] in Serum

Active

Part Descriptions

LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease Source: Regenstrief LOINC

LP66950-4 Betula verrucosa recombinant (rBet v) 2
Bet V 2 (also called Profilin) is birch pollen allergen -which like Bet V1 is cross-reactive with similar proteins from many fruits and vegetables including potatoes and mugwort .The respiratory tract is probably initial route of sensitization. Source: Regenstrief Institute

LP66950-4 Betula verrucosa recombinant (rBet v) 2
Recombinant non-glycosylated protein produced in an E. coli strain carrying a cloned cDNA encoding Betula verrucosa allergen Bet v 1

Bet v 2, a well-described minor allergen from birch pollen, belongs to the family of profilins, a group of common actin-binding proteins. Profilins can be found as cross-reactive allergens not only in pollen from unrelated plants (trees, grasses, weeds) but also in other plant tissues (of fruits, vegetables, nuts, spices, and latex). Copyright Copyright © 2006 Phadia AB. Source: ImmunoCap, ImmunoCap

LOINC Names Get Info

Fully-Specified Name: Betula verrucosa recombinant (rBet v) 2 Ab.IgG4:MCnc:Pt:Ser:Qn:
Long Common Name: Silver Birch recombinant (rBet v) 2 IgG4 Ab [Mass/volume] in Serum
Short Name: Silver Birch (rBet v) 2 IgG4-mCnc
Display Name: Silver Birch recombinant (rBet v) 2 IgG4 (S) [Mass/Vol]
Consumer Name Alpha Get Info: Silver birch recombinant (rBet v) 2 IgG4 antibody

Part Model Get Info

Component
Betula verrucosa recombinant (rBet v) 2 Ab.IgG4
LP430164-6
- Analyte
  Betula verrucosa recombinant (rBet v) 2 Ab.IgG4
  LP430164-6
  - Component Numerator
    Betula verrucosa recombinant (rBet v) 2 Ab.IgG4
    LP430164-6
    - Component Numerator Core
      Betula verrucosa recombinant (rBet v) 2
      LP66950-4
    - Component Numerator Core Suffix
      Ab.IgG4
      LP32397-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: ALLERGY
Type: Laboratory
First Released: Version 2.72
Last Updated: Version 2.72 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Betula verrucosa rekombinantní (rBet v) 2 Ab.IgG4:Hmotnostní koncentrace:Časový bod:Sérum:Kvantitativní:
el-GR	Greek (Greece)	Ανασυνδυασμένη Betula verrucosa (Σημύδα) (rBet v) 2 Ab.IgG4:MCnc:Pt:Ορός:Qn: Synonyms: Ab.IgG4 ALLERGY Betula verrucosa (Σημύδα) MCnc Pt Qn V Ανασυνδυασμένη Betula verrucosa (Σημύδα) (rBet v) 2 Αντίσωμα Ορός
es-ES	Spanish (Spain)	Betula verrucosa recombinante (rBet v2 Profilina) IgG4:Concentración de masa:Punto temporal:Suero:Qn: Synonyms: Cuantitativo
fr-CA	French (Canada)	Allergène recombinant (rBet v) 2 de Betula verrucosa, IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-BE	French (Belgium)	Allergène recombinant (rBet v) 2 de Betula verrucosa Anticorps. IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif: Synonyms: Anticorps Bouleau argenté, t3 t216
fr-FR	French (France)	Bouleau blanc rBet v2 (recombinant) Ac IgG4:Masse/Volume:Ponctuel:Sérum:Numérique:
it-IT	Italian (Italy)	Betula verrucosa, ricombinante (rBet v) 2 Ab.IgG4:MCnc:Pt:Siero:Qn: Synonyms: Anticorpi IgG4 anticorpo Betulla verrucosa (Betula verrucosa) Concentrazione di Massa Punto nel tempo (episodio) Ricombinante (rBet v) 2 di Betula verrucosa (Betul Risposta agli antigeni Siero
nl-NL	Dutch (Netherlands)	Betula verrucosa recombinant (rBet v) 2 As.IgG4:massa/volume:moment:serum:kwantitatief: Synonyms: antistof; antilichaam ruwe berk
pl-PL	Polish (Poland)	Betula verrucosa rekombinowana komponenta alergenowa (rBet v) 2 Ab.IgG4:stężenie masowe:punkt w czasie:surowica:ilościowy: Synonyms: Brzoza brodawkowata;Brzoza zwisła Rekombinowana komponenta alergenowa (rBet v) 2 brzozy brodawkowatej
ru-RU	Russian (Russian Federation)	Betula verrucosa рекомбинантный (rBet v) 2 Ат.IgG4:МассКонц:ТчкВрм:Сыв:Колич: Synonyms: Антитело Берёза повислая (Betula verrucosa) Берёза повислая (Betula verrucosa) рекомбинантный (rBet v) 2 Количественный Массовая концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Betula verrucosa rekombinant (rBet v) 2 Ab.IgG4:KütlKons:Zmlı:Ser:Kant: Synonyms: Ak Ak.IgG4 Huş ağacı
zh-CN	Chinese (China)	白桦树重组 (rBet v) 2 抗体.IgG4:质量浓度:时间点:血清:定量型: Synonyms: Ⅱ Ab.IgG4;IgG4;抗体 IgG4 Ab;自身抗体 II V 型可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 疣皮桦;银桦

Example Units

Unit	Source
mg/L	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=99452-5

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.