Description

Fibroblast growth factor 19 (FGF-19), is encoded by the FGF19 gene. It binds to fibroblast growth factor receptor 4 and is involved in adipocyte glucose uptake and the suppression of bile acid biosynthesis. [UniProt: O95750] FGF-19 is fully active in the presence of a cofactor - beta-Klotho protein. FGF-19 is created after every meal and plays a role in increasing glucose tolerance and insulin sensitivity and decreasing gluconeogenesis. Obesity in adults and non-alcoholic fatty liver disease in obese adolescents is associated with lower levels of FGF-19, while patients on hemodialysis have higher FGF-19 levels compared to the healthy population. PMID: 30927227
Source: Regenstrief LOINC

Basic Part Properties

Part Name
Fibroblast growth factor 19
Part Display Name
Fibroblast growth factor 19
Part Type
Component (Describes the core component or analyte measured)
Created On
2021-03-05
Construct for LOINC Short Name
FGF-19

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP422763-5

Language Variants Get Info

TagLanguageTranslation
fr-FRFrench (France)FGF-19
it-ITItalian (Italy)Fibroblasto 19, fattore di crescita
nl-NLDutch (Netherlands)fibroblastgroeifactor 19
es-ESSpanish (Spain)Factor de crecimiento de fibroblastos 19
zh-CNChinese (China)成纤维细胞生长因子 19
Synonyms: FGF-19;FGF19;纤维母细胞生长因子 19
pl-PLPolish (Poland)Czynnik wzrostu fibroblastów 19
Synonyms: FGF 19
el-GRGreek (Greece)Αυξητικός παράγοντας ινοβλαστών 19
Synonyms: Αυξητικός παράγοντας ινοβλαστών 19