LP422763-5
Fibroblast growth factor 19
Active
Description
Fibroblast growth factor 19 (FGF-19), is encoded by the FGF19 gene. It binds to fibroblast growth factor receptor 4 and is involved in adipocyte glucose uptake and the suppression of bile acid biosynthesis. [UniProt: O95750] FGF-19 is fully active in the presence of a cofactor - beta-Klotho protein. FGF-19 is created after every meal and plays a role in increasing glucose tolerance and insulin sensitivity and decreasing gluconeogenesis. Obesity in adults and non-alcoholic fatty liver disease in obese adolescents is associated with lower levels of FGF-19, while patients on hemodialysis have higher FGF-19 levels compared to the healthy population. PMID: 30927227
Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Fibroblast growth factor 19
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2021-03-05
- Construct for LOINC Short Name
- FGF-19
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| it-IT | Italian (Italy) | Fibroblasto 19, fattore di crescita |
| nl-NL | Dutch (Netherlands) | fibroblastgroeifactor 19 |
| es-ES | Spanish (Spain) | Factor de crecimiento de fibroblastos 19 |
| zh-CN | Chinese (China) | 成纤维细胞生长因子 19 Synonyms: FGF-19; |
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