LOINC
Version 2.73

100841-6Zinc finger protein of the cerebellum 4 Ab [Presence] in Cerebral spinal fluid by Line blotActive

Part Description

LP34979-2   Zinc finger protein of the cerebellum 4
Paraneoplastic neurological syndrome (PNS) is an autoimmune disorder that is manifested by progressive central, peripheral and/or autonomic nervous system symptoms. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The antibodies that attack the neural tissue develop in response to tumor cells. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed.[PMID:22412264] Of patients positive for the zinc finger protein of the cerebellum 4 (Zic4) antibodies, ninety-two percent were diagnosed with small cell lung cancer. Zic4 antibodies often occur concurrently with Hu and CRMP5 antibodies.[PMID: 15007130 Source: Regenstrief LOINC

Fully-Specified Name

Component
Zinc finger protein of the cerebellum 4 Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
Line blot

Additional Names

Short Name
Zic4 Ab CSF Ql Line blot
Display Name
Zinc finger protein of the cerebellum 4 Ab Line blot Ql (CSF)
Consumer Name Alpha
Zinc finger protein of the cerebellum 4 antibody, Spinal fluid

Example Answer List LL5435-4

Source: Integrating the Healthcare Enterprise - Japan

Answer Code Score Answer ID
Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value) 1 LA9633-4
Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value) 0 LA9634-2

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.73
Last Updated
Version 2.73
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
小脑锌指蛋白 4 抗体:存在情况或阈值:时间点:脑脊液:序数型:线点印迹法
nl-NLDutch (Netherlands)
zinc finger proteïne of the cerebellum 4 As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:lijnblot
fr-CAFrench (Canada)
Protéine à doigt de zinc du cervelet 4 , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunoessai sur bandelette
it-ITItalian (Italy)
Zinc finger, proteina del cervelletto 4 Ab:PrThr:Pt:LCS:Ord:Line blot
es-ESSpanish (Spain)
Proteína dedo de zinc del cerebelo 4 Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=100841-6