101418-2

Microorganism level similarity to reference sample [Score] in Isolate or Specimen by MS.MALDI-TOF

Active

Term Description

The level of similarity score indicates how similar the result from an unknown sample is to a reference sample. A higher score indicates that identification is possible at the species level, versus an intermediate score that allows identification at the genus level. Low scores do not allow identification of the organism from the unknown sample. The specific scores at which genus- and species-level identification is possible vary by microorganism. PMID: 28143403

Part Description

LP186074-3 MS.MALDI-TOF
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. PMID: 23824373 Source: Regenstrief LOINC, PMID: 23824373

LOINC Names Get Info

Fully-Specified Name: Microorganism level of similarity to reference sample:Score:Pt:Isolate/Specimen:Qn:MS.MALDI-TOF
Long Common Name: Microorganism level similarity to reference sample [Score] in Isolate or Specimen by MS.MALDI-TOF
Short Name: Microorg lvl sim ref smpl Islt/Spm M
Display Name: Microorganism level similarity to reference sample MS.MALDI-TOF (Islt/Spec) [Score]
Consumer Name Alpha Get Info: Microorganism level similarity to reference sample

Part Model Get Info

Component
Microorganism level of similarity to reference sample
LP434523-9
- Analyte
  Microorganism level of similarity to reference sample
  LP434523-9
  - Component Numerator
    Microorganism level of similarity to reference sample
    LP434523-9
    - Component Numerator Core
      Microorganism level of similarity to reference sample
      LP434523-9
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Score
LP185820-0
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate/Specimen
LP266970-5
- System Core
  Isolate/Specimen
  LP266970-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
MS.MALDI-TOF
LP186074-3

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.74
Last Updated: Version 2.75 (MIN)
Order vs. Observation: Observation

Formula (Readable)

Numerical score value ranged 0-3

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Mikroorganismus podobnost s referenčním vzorkem na úrovni mikroorganismů:Skóre:Časový bod:Izolát/vzorek:Kvantitativní:Hmotnostní spektrometrie.MALDI-TOF
el-GR	Greek (Greece)	Επίπεδο ομοιότητας μικροοργανισμού με δείγμα αναφοράς:Βαθμολογία:Pt:Απομονωθέν στέλεχος/Δείγμα:Qn:MS.MALDI-TOF Synonyms: MICRO MS.MALDI-TOF Pt Qn Απομονωθέν στέλεχος/Δείγμα Απομονωμένο στέλεχος Βαθμολογία Δείγμα Επίπεδο ομοιότητας μικροοργανισμού με δείγμα αναφοράς Μικροοργανισμός
es-ES	Spanish (Spain)	Nivel de similitud del microorganismo con la muestra de referencia:Puntuación:Punto temporal:Muestra aislada:Qn:MS.MALDI-TOF Synonyms: Cuantitativo
fr-FR	French (France)	Niveau de similitude du micro-organisme avec l'échantillon de référence:Score:Ponctuel:Isolat/échantillon:Numérique:Spectrométrie MALDI-TOF
it-IT	Italian (Italy)	Livello di somiglianza del microrganismo al campione di riferimento:Punteggio:Pt:Isolato/Campione:Qn:MS.MALDI-TOF Synonyms: Isolato o Campione Microbiologia Punto nel tempo (episodio)
pl-PL	Polish (Poland)	Poziom podobieństwa mikroorganizmów do próbki referencyjnej:liczba punktów:punkt w czasie:szczep/izolat lub próbka:ilościowy:spektrometria mas.MALDI-TOF Synonyms: Mikroorganizm
zh-CN	Chinese (China)	微生物与参考样品的相似性水平:评分:时间点:分离株/标本:定量型:MS.MALDI-TOF Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分值;得分;分数分离株/标本（样本、样品、试样）分离物;分离菌;分离菌株;隔离种群受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺基质辅助激光解吸/电离飞行时间质谱;基质辅助激光解吸电离飞行时间质谱;基质辅助激光解吸飞行时间质谱;基质辅助激光解析电离飞行时间质谱;Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry;MALDI-TOF-MS;Matrix-assisted laser desorption ionization-time of flight 微生物与参考样品的相似性水平（相似程度、类似程度）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间样品样本程度等级级级别试样

Example Units

Unit	Source
{score}	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101418-2

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.