Version 2.77

Part Description

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Component
Bran wheat Ab.IgG4
Property
PrThr
Time
Pt
System
Ser
Scale
SemiQn
Method
RAST

Additional Names

Short Name
Wheat Bran IgG4 RAST
Display Name
Wheat Bran IgG4 RAST (S) [Presence]
Consumer Name Alpha Get Info
Wheat bran IgG4 antibody

Example Answer List: LL1927-4

Source: Wikipedia
Link to External List
http://en.wikipedia.org/wiki/RAST_test
Answer Code Score Answer ID
0 LA6111-4
1 LA6112-2
2 LA6113-0
3 LA6114-8
4 LA6115-5
5 LA10137-0
6 LA10138-8

Basic Attributes

Class
ALLERGY
Type
Laboratory
First Released
Version 2.75
Last Updated
Version 2.75
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Salvado de trigo IgG4:PrThr:Punto temporal:Suero:Semicuantitativo:Prueba de absorcion de radioalergeno (RAST)
Synonyms: Semicuantitativo
fr-CA French (Canada) Son de blé , IgG4:Présence-Seuil:Temps ponctuel:Sérum:SemiQn:RAST
it-IT Italian (Italy) Crusca di frumento Ab.IgG4:PrThr:Pt:Siero:SemiQn:RAST
Synonyms: Anticorpi IgG4 anticorpo Crusca di frumento Presenza o Soglia Punto nel tempo (episodio) Risposta agli antigeni Siero Test di radioallergoassorbimento (RAST)
nl-NL Dutch (Netherlands) tarwezemelen As.IgG4:aanwezigheid:moment:serum:semikwantitatief:RAST
Synonyms: antistof; antilichaam radioallergosorbent test
zh-CN Chinese (China) 麦麸 抗体.IgG4:存在情况或阈值:时间点:血清:半定量型:放射过敏原吸附试验法
Synonyms: Ab.IgG4;IgG4;抗体 IgG4 Ab;自身抗体 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 放射过敏原吸附试验;放射过敏原吸附试验（Radioallergosorbent Test，RAST） 时刻;随机;随意;瞬间 麦糠;麸皮 麦麸 Ab

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=102927-1