Version 2.78

104832-1 Skin IgG Ab [Presence] in Serum by Human split skin substrate

Fully-Specified Name

Component
Skin Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Human split skin substrate

Additional Names

Short Name
Skin IgG Ser Ql Human split skin sub
Display Name
Skin IgG Human split skin substrate Ql (S)
Consumer Name Alpha Get Info
Skin IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
104835-4 Intercellular substance and basement membrane Ab.IgG panel - Serum

Member of these Groups Get Info

LOINC Group Group Name
LG26595-5 Skin Ab.IgG|PrThr|Pt|ANYBldSerPl

66881-4 Skin IgG Ab [Presence] in Serum by Monkey esophagus substrate

Term Description

The detection of skin antibodies assists in the diagnosis of chronic vesicular-bullous diseases such as pemphigus and pemphigoid. When patient sera are incubated on monkey or guinea pig esophagus sections, anti-skin antibodies present in the serum will bind with disease-specific patterns by immunofluorescence. For example, the intercellular (IC) antibody pattern diagnoses pemphigus with a 90% sensitivity. Testing with the 2 different species of esophagus sections (monkey and guinea pig) assists in distinguishing different forms of pemphigus. Antibodies following a basement membrane pattern are present in bullous pemphigoid (70%), vesicular pemphigoid (50%) and cicatricial pemphigoid (10%).
Source: Regenstrief LOINC

Fully-Specified Name

Component
Skin Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Monkey esophagus substrate

Additional Names

Short Name
Skin IgG Ser Ql Monkey esoph
Display Name
Skin IgG Monkey esophagus substrate Ql (S)
Consumer Name Alpha Get Info
Skin IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
7157

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
104835-4 Intercellular substance and basement membrane Ab.IgG panel - Serum

Member of these Groups Get Info

LOINC Group Group Name
LG26595-5 Skin Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Piel Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Sustrato de esófago de mono
es-ES Spanish (Spain) Piel IgG:PrThr:Punto temporal:Suero:Ord:Sustato del esófago de monos
fr-FR French (France) Peau anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Substrat oesophage de singe
fr-CA French (Canada) Peau, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Substrat oesophage de singe
it-IT Italian (Italy) Pelle Ab.IgG:PrThr:Pt:Siero:Ord:Substrato esofago scimmia
Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Substrato di esofago di scimmia
nl-NL Dutch (Netherlands) huid As.IgG:aanwezigheid:moment:serum:ordinaal:apen-oesofagussubstraat
Synonyms: antistof; antilichaam
tr-TR Turkish (Turkey) Deri Ab.IgG:MevcEşik:Zmlı:Ser:Srl:Maymun özefagus substratı
Synonyms: Ak Ak.IgG Mevcut
zh-CN Chinese (China) 皮肤 抗体.IgG:存在情况或阈值:时间点:血清:序数型:猴食管底物法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 猴食管底物;猴食道底物;猴子食管底物 皮;肤;表皮 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

104836-2 Basement membrane IgG Ab [Titer] in Serum by Immunofluorescence

Part Descriptions

LP14903-6   Basement membrane
The basement membrane is a thin sheet of fibers that underlies the epithelium, which lines the cavities and surfaces of organs including skin, or the endothelium, which lines the interior surface of blood vessels.
The primary function of the basement membrane is to anchor down the epithelium to its loose connective tissue underneath. This is achieved by cell-matrix adhesions through substrate adhesion molecules. A group of diseases stemming from improper function of basement membrane zone are united under the name epidermolysis bullosa. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Basement membrane (Wikipedia)

LP14903-6   Basement membrane
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Basement membrane Ab.IgG
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method
IF

Additional Names

Short Name
BM IgG Titr Ser IF
Display Name
Basement membrane IgG IF (S) [Titer]
Consumer Name Alpha Get Info
Basement membrane IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
104835-4 Intercellular substance and basement membrane Ab.IgG panel - Serum

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Membrana basal IgG:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
fr-CA French (Canada) Membrane basale, IgG:Titre:Temps ponctuel:Sérum:SemiQn:Immunofluorescence
it-IT Italian (Italy) Membrana basale Ab.IgG:Titr:Pt:Siero:SemiQn:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NL Dutch (Netherlands) basaalmembraan As.IgG:titer:moment:serum:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam IF
zh-CN Chinese (China) 基底膜 抗体.IgG:滴定度:时间点:血清:半定量型:免疫荧光法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 Goodpastures样综合征;Goodpastures病;肺出血-肾炎综合征;肾小球基底膜 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 免疫球蛋白 G 基底膜 Ab 基底膜 Ab.IgG 基底膜 IgG 抗基底膜 抗肾小球基底膜 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 肾小球基底膜 Ab 肾小球基底膜 Ab.IgG 肾小球基底膜 IgG 肾小球基底膜抗体 肾小球基底膜抗体.IgG 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

Example Units

Unit Source
{titer} Example UCUM Units

104831-3 Intercellular substance IgG Ab [Titer] in Serum by Immunofluorescence

Part Descriptions

LP14904-4   Intercellular substance
Intercellular substance (ICS) antibodies are antibodies to any one of several intercellular antigens, including the desmosomal cadherins desmoglein 1 and 3, and desmocollin 1, 2, and 3, which play a role in cell to cell adhesion. ICS antibodies, especially of type IgG, are associated with paraneoplastic pemphigus (PNP), also known as paraneoplastic autoimmune multiorgan syndrome (PAMS), as well as with other forms of pemphigus including pemphigus foliaceus and pemphigus vulgaris. ICS antibody deposition has a characteristic web- or honeycomb-like fluorescent pattern. PMID: 31214197 Source: Regenstrief LOINC

Fully-Specified Name

Component
Intercellular substance Ab.IgG
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method
IF

Additional Names

Short Name
ICS IgG Titr Ser IF
Display Name
Intercellular substance IgG IF (S) [Titer]
Consumer Name Alpha Get Info
Intercellular substance IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
104835-4 Intercellular substance and basement membrane Ab.IgG panel - Serum

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Sustancia intercelular IgG:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
fr-CA French (Canada) Matière intercellulaire, IgG:Titre:Temps ponctuel:Sérum:SemiQn:Immunofluorescence
it-IT Italian (Italy) Sostanza intercellulare Ab.IgG:Titr:Pt:Siero:SemiQn:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NL Dutch (Netherlands) intercellulaire substantie As.IgG:titer:moment:serum:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam IF
zh-CN Chinese (China) 细胞间质 抗体.IgG:滴定度:时间点:血清:半定量型:免疫荧光法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 ICS;天泡疮;天疱疮;细胞间结构;细胞间结构(Intercellular structure,ICS);细胞间质(Intercellular Substance,ICS);胞间结构 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 免疫球蛋白 G 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 细胞间质 Ab 细胞间质 Ab.IgG 细胞间质 IgG 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类 质

Example Units

Unit Source
{titer} Example UCUM Units