108876-4
Rabies virus neutralizing antibody [Measurement] in Serum
Trial
Status Information
- Status
- TRIAL
Term Description
This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6
Part Descriptions
LP16737-6 Rabies virus
Rabies virus (RV), is an enveloped, single-stranded, negative sense RNA virus and a member of the Rhabdoviridae family. It is transmitted when an animal infected with RV bites an individual or the saliva from an infected animal comes into contact with an open wound. Once RV penetrates the muscle or connective tissue it begins to replicate and then infiltrates the peripheral nerves through the neuromuscular junction. From there, RV spreads to the central nervous system (CNS) in the endoneurium of the Schwann cells. If bitten by an animal that may have RV infection, rabies immune globulin and rabies vaccine should be administered. Otherwise, there is no treatment for infection by RV other than supportive care, and acute infection of the CNS is almost always fatal. In countries where preventative care is not practiced, RV is still widespread. In Asia, 30,000 people die annually from RV infection. Diagnosis of RV is done on two tissue specimens from the brain that are analyzed by direct fluorescent antibody (DFA), mouse inoculation, tissue culture and polymerase chain reaction.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307483/
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP447904-6 {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Rabies virus Ab.Neut:
{Measurement}: -: Ser: -: - Long Common Name
- Rabies virus neutralizing antibody [Measurement] in Serum
- Short Name
- RABV NAb Msmt Ser
- Display Name
- Rabies virus neut ab (S) [Measurement]
- Consumer Name Alpha Get Info
- Rabies virus neutralizing antibody, Blood
Part Model Get Info
- Component
- Rabies virus Ab.Neut
LP430462-4
- Analyte
- Rabies virus Ab.Neut
LP430462-4
- Component Numerator
- Rabies virus Ab.Neut
LP430462-4
- Component Numerator Core
- Rabies virus
LP16737-6
- Component Numerator Core Suffix
- Ab.Neut
LP207365-0
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- {Measurement}
LP447904-6
- Time
- -
LP70420-2
- Time Core
- -
LP70420-2
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- -
LP7747-1
- Method
- NULL
Basic Attributes
- Class
- LABORDERS.ONTOLOGY
- Type
- Laboratory
- First Released
- Version 2.81
- Last Updated
- Version 2.81 (ADD)
- Order vs. Observation
- Order
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Virus de la Rabia Anticuerpos antineutrófilos: |
| fr-FR | French (France) | Rage virus Ac neutralisant: |
| it-IT | Italian (Italy) | Rabbia, virus Ab.Neut: Synonyms: anticorpo Codici richieste di laboratorio LABORDERS.ONTOLOGY Misurazione Siero Virus della rabbia |
| pl-PL | Polish (Poland) | Wirus wścieklizny Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa wścieklizny Przeciwciała neutralizujące do wirusa wścieklizny |
| zh-CN | Chinese (China) | 狂犬病病毒 抗体.中和: Synonyms: {测量}; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://