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Part Descriptions

LP36028-6   Cocaine+Benzoylecgonine
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. PMID: 8761012 Source: Regenstrief LOINC

LP36028-6   Cocaine+Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is a biological metabolite with a stable structure that resists hydrolysis, both in the body and in the environment. Benzoylecgonine remains in the body for a few days and is commonly used as a marker in drug tests. [PMCID:1929267] PMID: 27224254 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Cocaine+Benzoylecgonine:PrThr:Pt:Tiss:Ord:Mass Spec
Long Common Name
Cocaine+Benzoylecgonine [Presence] in Tissue by Mass Spectrometry
Short Name
Cocaine+BZE Tiss Ql Mass Spec
Display Name
Cocaine+Benzoylecgonine Mass Spec Ql (Tiss)
Consumer Name Alpha Get Info
Cocaine+Benzoylecgonine, Tissue

Part Model Get Info

  • Component
    Cocaine+Benzoylecgonine
    LP36028-6
    • Analyte
      Cocaine+Benzoylecgonine
      LP36028-6
      • Component Numerator
        Cocaine+Benzoylecgonine
        LP36028-6
        • Component Numerator Core
          Cocaine+Benzoylecgonine
          LP36028-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Mass Spec
    LP451714-2

Example Answer List: LL744-4

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
DetectedLA11882-0
Not detectedLA11883-8

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.83
Last Updated
Version 2.83 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG52779-2Cocaine+Benzoylecgonine|PrThr|Pt|Tiss

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=113435-2