113440-2
Cocaine+Benzoylecgonine [Presence] in Serum or Plasma
Active
Part Descriptions
LP36028-6 Cocaine+Benzoylecgonine
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. PMID: 8761012
Source: Regenstrief LOINC
LP36028-6 Cocaine+Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is a biological metabolite with a stable structure that resists hydrolysis, both in the body and in the environment. Benzoylecgonine remains in the body for a few days and is commonly used as a marker in drug tests. [PMCID:1929267] PMID: 27224254
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Cocaine+Benzoylecgonine:
PrThr: Pt: Ser/Plas: Ord: - Long Common Name
- Cocaine+Benzoylecgonine [Presence] in Serum or Plasma
- Short Name
- Cocaine+BZE SerPl Ql
- Display Name
- Cocaine+Benzoylecgonine Ql
- Consumer Name Alpha Get Info
- Cocaine+Benzoylecgonine, Blood
Part Model Get Info
Example Answer List: LL744-4
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.83
- Last Updated
- Version 2.83 (ADD)
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG52780-0 | Cocaine+Benzoylecgonine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Κοκαΐνη+Βενζοϋλεκγονίνη: Synonyms: DRUG/TOX Ord PrThr Pt Βενζοϋλεκγονίνη Κοκαΐνη Κοκαΐνη+Βενζοϋλεκγονίνη Ορός Ορός/Πλάσμα Πλάσμα |
| es-ES | Spanish (Spain) | Cocaina+Benzoilecgonina: |
| fr-BE | French (Belgium) | Cocaïne+Benzoylecgonine: |
| fr-CA | French (Canada) | Cocaïne+Benzoylecgonine: |
| fr-FR | French (France) | Cocaïne+benzoylecgonine: |
| it-IT | Italian (Italy) | Cocaina+Benzoilecgonina: Synonyms: Livelli farmacologici e tossicologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | cocaïne + benzoylecgonine: |
| pl-PL | Polish (Poland) | Kokaina+Benzoiloekgonina: |
| ru-RU | Russian (Russian Federation) | Кокаин+Бензоилэкгонин: Synonyms: Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Kokain+Benzoilekgonin: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 可卡因+苯甲酰芽子碱: Synonyms: C17H21NO4; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://