23373-4
Porcine respiratory coronavirus neutralizing antibody [Presence] in Serum by Neutralization test
Active
Part Descriptions
LP19934-6 Porcine respiratory coronavirus
Porcine respiratory coronavirus (PRCV) is a mutant strain of transmissible gastroenteritis virus causing mild or subclinical respiratory infections in young swine. Research has shown that the primary cells infected with PRCV are epithelial cells of the bronchioles, type II pneumocytes, and alveolar and septal macrophages. PMID: 9191988 Potential targets when testing for PRCV RNA include a region of the nucleocapsid protein (N) gene and the spike (S) gene.
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Porcine respiratory coronavirus Ab.Neut:
PrThr: Pt: Ser: Ord: Neut - Long Common Name
- Porcine respiratory coronavirus neutralizing antibody [Presence] in Serum by Neutralization test
- Short Name
- PRCoV NAb Ser Ql Nt
- Display Name
- Porcine respiratory coronavirus neut ab Neut test Ql (S)
- Consumer Name Alpha Get Info
- Porcine respiratory coronavirus neutralizing antibody, Blood
Part Model Get Info
- Component
- Porcine respiratory coronavirus Ab.Neut
LP430454-1
- Analyte
- Porcine respiratory coronavirus Ab.Neut
LP430454-1
- Component Numerator
- Porcine respiratory coronavirus Ab.Neut
LP430454-1
- Component Numerator Core
- Porcine respiratory coronavirus
LP19934-6
- Component Numerator Core Suffix
- Ab.Neut
LP207365-0
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- PrThr
LP217195-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- Ord
LP7751-3
- Method
- Neut
LP6416-4
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 1.0n
- Last Updated
- Version 2.72 (NAM)
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Respirační koronavirus prasat (PRCV) Ab.neutralizační: |
| el-GR | Greek (Greece) | Αναπνευστικός κορωνοϊός των χοίρων Ab.Neut: Synonyms: Ab.Neut MICRO Ord PrThr Pt Αναπνευστικός κορωνοϊός των χοίρων Αντίσωμα Κορωνοϊός Ορός Ουδετερόφιλα Των χοίρων |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] coronavirus respiratorio porcino [Ac]: |
| es-ES | Spanish (Spain) | Coronavirus porcino respiratorio Anticuerpos antineutrófilos: |
| es-MX | Spanish (Mexico) | Coronavirus respiratorio porcino Ab: |
| fr-CA | French (Canada) | Coronavirus respiratoire porcin Ac.neut: |
| it-IT | Italian (Italy) | Coronavirus respiratorio suino Ab.Neut: Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione |
| ko-KR | Korean (Korea, Republic Of) | 돼지 호흡 코로나바이러스 항체: |
| nl-NL | Dutch (Netherlands) | 'porcine' respiratoir coronavirus As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Świński koronawirus oddechowy Ab.Neutralizujące: Synonyms: Koronawirus Przeciwciała do koronawirusa Przeciwciała do świńskiego koronawirusa oddechowego Przeciwciała neutralizujące do świńskiego koronawirusa oddechowego |
| pt-BR | Portuguese (Brazil) | Coronavírus respiratório porcino Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 猪呼吸道冠状病毒 抗体.中和: Synonyms: Ab; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://