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Part Descriptions

LP19950-2   Transmissible gastroenteritis virus
Transmissible gastroenteritis virus (TGEV) is a coronovirus which causes an acute viral disease of swine. It is a common diarrheal virus in pigs of all ages. Jejunal and ileal villous epithelial cells are infected and destroyed by the virus. It is extremely fatal to pigs under 3 weeks old, with mortality rates decreasing with age. It is characterized by diarrhea and vomiting. TGEV can also exist in an endemic form in swine herds where either partial immunity or a concurrent porcine respiratory coronavirus (PRCV) infection is present. Since PRCV shares antibody neutralizing epitopes with TGEV, it acts like a vaccine against TGEV, making the disease less severe and causing lower mortality.
PMID: 16716052 Source: National Library of Medicine, MeSH 2006

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Transmissible gastroenteritis virus Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name
Transmissible gastroenteritis virus neutralizing antibody [Titer] in Serum by Neutralization test
Short Name
TGEV NAb Titr Ser Nt
Display Name
Transmissible gastroenteritis virus neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info
Transmissible Gastroenteritis virus neutralizing antibody, Blood

Part Model Get Info

  • Component
    Transmissible gastroenteritis virus Ab.Neut
    LP430479-8
    • Analyte
      Transmissible gastroenteritis virus Ab.Neut
      LP430479-8
      • Component Numerator
        Transmissible gastroenteritis virus Ab.Neut
        LP430479-8
        • Component Numerator Core
          Transmissible gastroenteritis virus
          LP19950-2
        • Component Numerator Core Suffix
          Ab.Neut
          LP207365-0
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    Neut
    LP6416-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0n
Last Updated
Version 2.75 (MAJ)
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus přenosné gastroenteritidy Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
el-GRGreek (Greece)Ιός μεταδοτικής γαστρεντερίτιδας Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα
Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Ιός μεταδοτικής γαστρεντερίτιδας Ορός Ουδετερόφιλα
es-ARSpanish (Argentina)[anticuerpo anti - ] virus de la gastroenteritis infecciosa [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ESSpanish (Spain)Virus de la gastroenteritis transmisible Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Virus de la gastroenteritis transmisible Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-CAFrench (Canada)Virus gastroentérite transmissible Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
fr-FRFrench (France)Gastroentérite transmissible virus Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
it-ITItalian (Italy)Gastroenterite trasmissibile, virus Ab.Neut:Titr:Pt:Siero:SemiQn:Neut
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Virus della gastroenterite trasmissibile
ko-KRKorean (Korea, Republic Of)전염성 위창자염 바이러스 항체:역가:검사시점:혈청:정량:중화
nl-NLDutch (Netherlands)overdraagbare gastro-enteritisvirus As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest
Synonyms: antistof; antilichaam
pl-PLPolish (Poland)Wirus zakaźnego zapalenia żołądka i jelit świń Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji
Synonyms: Przeciwciała do wirusa zakaźnego zapalenia żołąka i jelit świń Przeciwciała neutralizujące do wirusa zakaźnego zapalenia żołąka i jelit świń
pt-BRPortuguese (Brazil)Gastroenterite transmissível vírus Ac:Título:Pt:Soro:Qn:Teste de neutralização
Synonyms: ; TGEV; Coronavirus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CNChinese (China)传染性胃肠炎病毒 抗体.中和:滴定度:时间点:血清:半定量型:中和试验
Synonyms: Ab;自身抗体 TGEV Ab TGEV 抗体 TGEV;传染性胃肠炎;冠状病毒 中和试验;中和抗体;中和 传染性胃肠炎病毒 Ab 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=23492-2