Version 2.80

Part Descriptions

LP29176-2   Cyclic citrullinated peptide
Citrullinated peptide (CCP) is a naturally occurring protein that is produced during the metabolism of ornithine to arginine. CCP proteins are found in synovial tissue of patients with rheumatoid arthritis (RA). High levels of antibodies to CCP have a strong association with RA and are predictive of an aggressive and destructive disease outcome. CCP antibody tests can help diagnose RA when the rheumatoid factor (RF) is negative or below 50 IU/mL.(Pagana, Kathleen Deska, and Timothy James Pagana. Mosby's Manual of Diagnostic and Laboratory Tests. St. Louis, MO: Mosby/Elsevier, 2014. Print.) .) IgA to CCP is more elevated in patients with RA than levels found in healthy individuals or those with other rheumatic diseases. PMID: 18565246 Source: Regenstrief LOINC

LP37860-1   Cyclic citrullinated peptide Ab.IgG
Citrulline is a non-standard amino acid that can be incorporated into proteins only by modification of arginine during a variety of biologic processes including inflammation. Several citrullinated proteins have been demonstrated in the RA synovium. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease with a prevalence of 0.3 to 1% worldwide and leads to progressive joint erosion and disability if not treated early. Identifying citrullinated epitopes targets led to first and then second generation anti-cyclic citrullinated peptide (anti-CCP) antibody assays. These anti-CCP antibodies are important diagnostic and prognostic markers for rheumatoid arthritis (RA) as they: 1) may be more sensitive than RF (rheumatoid factor) in early and established disease, 2) may be a marker of erosive disease, and 3) may be found in healthy patients years prior to clinical onset, and 4) may predict development of undifferentiated arthritis into RA. PMID: 19427413 PMID: 17558653 Source: Regenstrief LOINC , PMID: 19427413

Fully-Specified Name

Component
Cyclic citrullinated peptide Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Long Common Name
Cyclic citrullinated peptide IgG Ab [Presence] in Serum
Short Name
cCP IgG Ser Ql
Display Name
Cyclic citrullinated peptide IgG Ql (S)
Consumer Name Alpha Get Info
Cyclic citrullinated peptide IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.73 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
6551

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cyclisches Citrullin-Peptid Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:
Synonyms: CCP
el-GR Greek (Greece) Κυκλικό κιτρουλλιωμένο πεπτίδιο Αντισώματα IgG:PrThr:Pt:Ορός:Ord:
Synonyms: PrThr Ανοσοσφαιρίνη G Κυκλικό κιτρουλλιωμένο πεπτίδιο
es-ES Spanish (Spain) Peptido cíclico citrulinado IgG:PrThr:Punto temporal:Suero:Ord:
es-MX Spanish (Mexico) Péptido cíclico citrulinado Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:
et-EE Estonian (Estonia) Tsükliline tsitrulleeritud peptiid antikehad.IgG:PrThr:Pt:S:Ord:
Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Peptide citrulliné cyclique, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FR French (France) Peptide cyclique citrulliné anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
fr-BE French (Belgium) Peptide citrulliné cyclique Anticorps. IgG:PrThr:Temps ponctuel:Sérum:Ordinal:
Synonyms: Anticorps CCP
it-IT Italian (Italy) Peptide ciclico citrullinato Ab.IgG:PrThr:Pt:Siero:Ord:
Synonyms: anticorpi IgG anticorpo CCP Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) Cyclic citrullinated peptide Antibody.immunoglobulin G:임의농도:검사시점:혈청:순위척도:
nl-NL Dutch (Netherlands) cyclisch citrulline-peptide As.IgG:aanwezigheid:moment:serum:ordinaal:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Peptídeo Cíclico Citrulinado Ac.IgG:ACnc:Pt:Soro:Ord:
Synonyms: Immune globulin G; Immunoglobulin G; cCP; Cyclic Citrulinated Peptide; CCP3; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Pept; Serology
ru-RU Russian (Russian Federation) Циклический цитруллинизированный пептид Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Siklik sitrülline peptid Ab.IgG:MevcEşik:Zmlı:Ser:Srl:
Synonyms: Mevcut
zh-CN Chinese (China) 环瓜氨酸肽 抗体.IgG:存在情况或阈值:时间点:血清:序数型:
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 cCP;CCP3;环瓜氨酸肽;Cyclic Citrullinated Peptide 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗环瓜氨酸肽 抗环瓜氨酸肽抗体 时刻;随机;随意;瞬间 环瓜氨酸肽 Ab 环瓜氨酸肽 Ab.IgG 环瓜氨酸肽 IgG 缩氨酸 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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