459-8
Streptomycin [Susceptibility] by Minimum lethal concentration (MLC)
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Part Descriptions
LP16282-3 Streptomycin
Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Streptomycin stops bacterial growth by damaging cell membranes and inhibiting protein synthesis. Specifically, it binds to the 23S rRNA molecule of the bacterial ribosome, which prevents the release of the growing protein (polypeptide chain). Humans have structurally different ribosomes than bacteria, thereby allowing the selectivity of this antibiotic for bacteria. Streptomycin cannot be given orally, but must be administered by regular intramuscular injection. An adverse effect of this medicine is ototoxicity. It can result in permanent hearing loss. History:It was first isolated on October 19, 1943 in the laboratory of Selman Abraham Waksman at Rutgers University by Albert Schatz, a graduate student in his laboratory.
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Source: Wikipedia, Streptomycin (Wikipedia)
LP16282-3 Streptomycin
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Streptomycin
- Property
- Susc
- Time
- Pt
- System
- Isolate
- Scale
- Qn
- Method
- MLC
Additional Names
- Short Name
- Streptomycin Islt MLC
- Display Name
- Streptomycin MLC [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Streptomycin
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.19
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 87927-0 | Bacterial susceptibility panel - Isolate by Minimum lethal concentration (MLC) |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG41111-2 | StreptomycinSusc| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Streptomycin: |
| es-AR | Spanish (Argentina) | estreptomicina: |
| es-ES | Spanish (Spain) | Estreptomicina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Estreptomicina: |
| et-EE | Estonian (Estonia) | Streptomütsiin: Synonyms: Isolaat Juhuslik Kvantitatiivne Minimaalne letaalne kontsentratsioon Tundlikkus |
| fr-CA | French (Canada) | Streptomycine: |
| fr-FR | French (France) | Streptomycine: |
| fr-BE | French (Belgium) | Streptomycine: |
| it-IT | Italian (Italy) | Streptomicina: Synonyms: Concentrazione minima letale (MLC) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici |
| ko-KR | Korean (Korea, Republic Of) | 스트렙토마이신: |
| nl-NL | Dutch (Netherlands) | streptomycine: Synonyms: MLC |
| pt-BR | Portuguese (Brazil) | Estreptomicina: Synonyms: Streptomyc; |
| tr-TR | Turkish (Turkey) | Streptomisin: |
| zh-CN | Chinese (China) | 链霉素: Synonyms: C21H39O12N7 分离物; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=459-8
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