49783-4

Onchocerca sp IgG4 Ab [Units/volume] in Serum by Immunoassay

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Part Descriptions

LP14830-1 Onchocerca sp
Onchocerca is a genus of nematode (roundworm) that includes O. volvulus, the causative agent of the human disease known as River Blindness. River blindness results in vision impairment and can also cause skin disease and debilitating itching. Onchocerciasis is the second-leading infectious cause of blindness in humans. https://www.cdc.gov/parasites/onchocerciasis/index.html Other species of Onchocerca include O. lupi, which can cause disease in dogs, cats, and humans, O. gutturosa and O. lienalis, which affect cattle, and O. cervicalis, which affects horses. Source: Regenstrief LOINC

LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Onchocerca sp Ab.IgG4:ACnc:Pt:Ser:Qn:IA
Long Common Name: Onchocerca sp IgG4 Ab [Units/volume] in Serum by Immunoassay
Short Name: Onchocerca IgG4 Ser IA-aCnc
Display Name: Onchocerca sp IgG4 IA Qn (S)
Consumer Name Alpha Get Info: Onchocerca sp IgG4 antibody, Blood

Part Model Get Info

Component
Onchocerca sp Ab.IgG4
LP174074-7
- Analyte
  Onchocerca sp Ab.IgG4
  LP174074-7
  - Component Numerator
    Onchocerca sp Ab.IgG4
    LP174074-7
    - Component Numerator Core
      Onchocerca sp
      LP14830-1
    - Component Numerator Core Suffix
      Ab.IgG4
      LP32397-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.22
Last Updated: Version 2.69 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Onchocerca sp IgG4:Arbitrární koncentrace:Časový bod:Sérum:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	Παράσιτο Onchocerca sp Ab.IgG4:ACnc:Pt:Ορός:Qn:IA Synonyms: Ab.IgG4 ACnc IA MICRO Pt Qn Αντίσωμα Ορός Παράσιτο Onchocerca sp
es-ES	Spanish (Spain)	Onchocerca sp IgG4:Concentración arbitraria:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Onchocerca sp Ab.IgG4:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Onchocerca sp antikehad.IgG4:Acnc:Pt:S:Qn:IA Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA	French (Canada)	Onchocerca sp, IgG4:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR	French (France)	Onchocerca Ac IgG4:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Onchocerca sp Anticorps. IgG4:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA Synonyms: Anticorps
it-IT	Italian (Italy)	Onchocerca sp Ab.IgG4:ACnc:Pt:Siero:Qn:IA Synonyms: Anticorpi IgG4 anticorpo Concentrazione Arbitraria Immunoassay Microbiologia Punto nel tempo (episodio) Siero
nl-NL	Dutch (Netherlands)	Onchocerca sp. As.IgG4:eenheid/volume:moment:serum:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
pt-BR	Portuguese (Brazil)	Onchocerca sp Ac.IgG4:ACnc:Pt:Soro:Qn:Imunoensaio Synonyms: Filariasis; River blindness; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; species; spp; Microbiology
ru-RU	Russian (Russian Federation)	Onchocerca sp Ат.IgG4:ПроизвКонц:ТчкВрм:Сыв:Колич:IA Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Onchocerca sp Ab.IgG4:SçKons:Zmlı:Ser:Kant:İA Synonyms: Ak Ak.IgG4 İmmünölçüm, immünoassay
zh-CN	Chinese (China)	盘尾属单个未知种抗体.IgG4:任意型浓度:时间点:血清:定量型:免疫测定法 Synonyms: Ab.IgG4;IgG4;抗体 IgG4 Ab;自身抗体 Onchocerciasis;丝虫病;河盲;河盲症;盘尾丝虫;盘尾丝虫属;盘尾丝虫病;盘尾科;瞎眼丝虫病;盘尾单个未知种任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间物种生物种盘尾丝虫 Ab 盘尾丝虫属 Ab 盘尾丝虫属抗体盘尾丝虫抗体盘尾属 Ab

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.