Version 2.78

Status Information

Status
DEPRECATED
Reason
Erroneous
Comment
Changed property, scale, and method from PrThr, Ord, Probe.amp to PRID, NOM, and Probe.amp.tar respectively to accurately represent the assay and answer list.
Map-To Long Common Name Mapping Guidance
82354-2 Human papilloma virus 16 and 18+45 E6+E7 mRNA [Identifier] in Cervix by NAA with probe detection

Term Description

Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16, 18, and 45 in cervical specimens from women with positive HPV assay results. For women 21-years and older with atypical squamous cells of undetermined significance (ASC-US) cervical cytology results, and HPV positive assay results, this assay can be used to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45. For women 30-years and older, the HPV 16, 18, and/or 45 genotype assay can be used to test samples from women with HPV assay positive results, along with cervical cytology results. This assay has not been evaluated for HPV vaccinated patients or in cases of suspected abuse. It differentiates HPV 16 from HPV 18 and/or HPV 45, but does not differentiate HPV 18 and HPV 45. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay which uses target capture, target amplification by transcription-mediated amplification and detection of the amplification products by hybridization protection.
Source: Regenstrief LOINC

Part Description

LP184364-0   Human papilloma virus 16 & 18+45 E6+E7 mRNA
A group of about 30 HPVs, typically transmitted through sexual contact. Genital HPV infection is very common, with estimates suggesting that up to 75% of women will become infected with one or more of the sexually transmitted HPV types at some point during adulthood (Baseman and Koutsky, 2005). Some sexually transmitted HPVs, such as types 6 and 11, can cause genital warts. However, most HPV types that infect the genitals tend not to cause noticeable symptoms. Persistent infection with a subset of about a dozen so-called high-risk sexually transmitted HPVs, including types 16,18,31, and 33, can lead to the development of anogenital cancers, including cervical, penile and anal. HPV infection is a necessary factor in the development of nearly all cases of cervical cancer (Walboomers 1999). Cervical Pap smear testing is used to detect HPV-induced cellular abnormalities. This allows targeted surgical removal of pre-cancerous lesions prior to the development of invasive cervical cancer. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Human papilloma virus (Wikipedia)

Fully-Specified Name

Component
Human papilloma virus 16 & 18+45 E6+E7 mRNA
Property
PrThr
Time
Pt
System
Cvx
Scale
Ord
Method
Probe.amp

Additional Names

Short Name
Deprecated HPV16+18+45 E6+E7mRNA Cervix
Display Name
HPV 16 and 18+45 E6+E7 mRNA Probe amp Ql (Cvx)
Consumer Name Alpha Get Info
HPV 16 and 18+45 E6+E7 MRNA, Cervix

Example Answer List: LL2997-6

Source: Ministry St. Michaels Hospital
Answer Code Score Answer ID
Negative - 16, Negative - 18/45 LA21378-7
Negative - 16, Positive - 16/45 LA21379-5
Positive - 16, Negative - 18/45 LA21380-3
Positive - 16, Positive - 18/45 LA21381-1
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.50
Last Updated
Version 2.58
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Papilomavirus humano 16 y 18+45 E6+E7 ARNm:PrThr:Punto temporal:Cuello uterino:Ord:Sondas de amplificación
es-MX Spanish (Mexico) Virus del papiloma humano 16 y 18 + 45 ARNm de E6 + E7:Presencia o umbral:Punto temporal:Cuello uterino:Ordinal:Sonda con amplificación
it-IT Italian (Italy) Papilloma virus umano 16 & 18+45 E6+E7 mRNA:PrThr:Pt:Cvx:Ord:Sonda.amp
Synonyms: Cervice uterina Microbiologia Papilloma virus umano 16 e 18 Papilloma virus umano 16 e 18+45 E6+E7 mRNA Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda di DNA
nl-NL Dutch (Netherlands) Humaan papillomavirus 16 & 18+45 E6+E7 mRNA:aanwezigheid:moment:cervix:ordinaal:probe.amplificatie
Synonyms: baarmoederhals
pl-PL Polish (Poland) Wirus brodawczaka ludzkiego 16 i 18+45 E6+E7 mRNA:granica wykrywalności:punkt w czasie:szyjka macicy:półilościowy:sonda z amplifikacją
Synonyms: mRNA onkoprotein E6+E7 wirusa brodawczaka ludzkiego typ 16 i 18+45 Wirus brodawczaka ludzkiego Wirus brodawczaka ludzkiego typ 16 Wirus brodawczaka ludzkiego typ 16 i 18 Wirus brodawczaka ludzkiego typ 16+18
tr-TR Turkish (Turkey) Human papilloma virüs 16 ve 18+45 E6+E7 mRNA:MevcEşik:Zmlı:Cvx:Srl:Prob.amf
Synonyms: Mevcut
zh-CN Chinese (China) 人乳头瘤病毒 16 与 18+45 E6+E7 mRNA:存在情况或阈值:时间点:子宫颈:序数型:探针法.基因扩增
Synonyms: HPV 16 & 18;HPV 16 & 18 型;HPV16 & 18;人类乳头瘤病毒 16 & 18 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV 16;HPV 16 型;HPV16;人类乳头瘤病毒 16 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV 16+18;HPV 16+18 型;HPV16+18;人类乳头瘤病毒 16+18 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV;人乳头瘤病毒（Human papilloma virus，HPV）;人类乳头瘤病毒;生殖器疣 人类乳头瘤病毒（HPV） 16 与 18+45 E6+E7 mRNA 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 宫颈;生殖道 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75406-9